Predictors of dementia amongst newly diagnosed non-valvular atrial fibrillation patients

Atrial fibrillation (AF) confers a 2-to-3-fold increased risk of developing cognitive dysfunction and dementia, independent of age and past stroke. The purpose of study was to identify risk factors for developing dementia amongst AF patients in India. This was a single-centre, prospective, observati...

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Bibliographic Details
Published in:Indian heart journal 2022-11, Vol.74 (6), p.505-509
Main Authors: Batta, Akash, Sharma, Yash Paul, Hatwal, Juniali, Panda, Prashant, Kumar, Budumuri Gautam Vinay, Bhogal, Sukhdeep
Format: Article
Language:English
Subjects:
Atrial fibrillation
Cognitive decline
Dementia
Research Brief
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Summary:Atrial fibrillation (AF) confers a 2-to-3-fold increased risk of developing cognitive dysfunction and dementia, independent of age and past stroke. The purpose of study was to identify risk factors for developing dementia amongst AF patients in India. This was a single-centre, prospective, observational study wherein recently diagnosed, treatment naïve, persistent non-valvular AF patients were enrolled. All patients were screened for dementia using the Mini-Mental state exam. Amongst a total of 108 patients enrolled, 40 (37%) had dementia. The most common cognitive deficits were in attention and calculation followed by memory deficits. Factors independently contributing to dementia were advanced age, female sex, presence of diabetes, elevated pulmonary artery pressures and a lower serum albumin.
ISSN:0019-4832
2213-3763
DOI:10.1016/j.ihj.2022.11.009