Salmonella subtypes with increased MICs for azithromycin in travelers returned to The Netherlands

Antimicrobial susceptibility was analyzed for 354 typhoidal Salmonella isolates collected during 1999-2012 in the Netherlands. In 16.1% of all isolates and in 23.8% of all isolates that showed increased MICs for ciprofloxacin, the MIC for azithromycin was increased. This resistance may complicate em...

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Bibliographic Details
Published in:Emerging infectious diseases 2014-04, Vol.20 (4), p.705-708
Main Authors: Hassing, Robert-Jan, Goessens, Wil H F, van Pelt, Wilfrid, Mevius, Dik J, Stricker, Bruno H, Molhoek, Nicky, Verbon, Annelies, van Genderen, Perry J J
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Azithromycin
Azithromycin - therapeutic use
ciprofloxacin
Ciprofloxacin - therapeutic use
Demographic aspects
Diagnosis
Dispatch
drug resistance
Drug Resistance, Bacterial - physiology
Drug therapy
enteric fever
Health aspects
Humans
in-vitro activity
india
Microbial Sensitivity Tests - methods
multidrug-resistant
Netherlands
ofloxacin
paratyphi
Patient outcomes
Salmonella
Salmonella - drug effects
Salmonella - isolation & purification
Salmonella Infections - drug therapy
Salmonella Infections - microbiology
susceptibility
Travel
travel medicine
Travelers
trial
typhi
Typhoid fever
Typhoid Fever - drug therapy
Typhoid Fever - microbiology
uncomplicated typhoid-fever
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Summary:Antimicrobial susceptibility was analyzed for 354 typhoidal Salmonella isolates collected during 1999-2012 in the Netherlands. In 16.1% of all isolates and in 23.8% of all isolates that showed increased MICs for ciprofloxacin, the MIC for azithromycin was increased. This resistance may complicate empirical treatment of enteric fever.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2004.131536