Dataset reporting detection of breast cancer-related HER2I655V polymorphism using allele-specific polymerase chain reaction

The dataset presented in this article is related to the research article entitled “Detection of HER2 Gene Polymorphism in Breast Cancer: PCR Optimization Study” (B.R. Budiarto, Desriani, 2016) [1] with some modification in primers used and in PCR optimization strategy to eliminate false-positive res...

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Bibliographic Details
Published in:Data in brief 2016-12, Vol.9 (C), p.689-695
Main Authors: Budiarto, Bugi Ratno, Desriani
Format: Article
Language:English
Subjects:
Allele-specific PCR
Breast cancer
Data
HER2
Ile655Val
Single nucleotide polymorphism
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Summary:The dataset presented in this article is related to the research article entitled “Detection of HER2 Gene Polymorphism in Breast Cancer: PCR Optimization Study” (B.R. Budiarto, Desriani, 2016) [1] with some modification in primers used and in PCR optimization strategy to eliminate false-positive result that may occur in HER2I655V polymorphism detection. Combining a new set of primers with PCR gradient, The allele-specific PCR well performs to detect all type of breast cancer-originated HER2I655V genotypes. The validation of this method was done using Sanger DNA sequencing, offering an alternative tool for HER2I655V polymorphism detection in another type of cancer.
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2016.09.033