Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole

To discover new 1,2,4-triazole derivatives which may possess significant biological activities, we synthesized a series of novel 6-aryl-3-(D-galactopentitol-1-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines and 4-(arylmethylidene)amino-5-(D-galactopentitol-1-yl)-3-mercapto-4H-1,2,4-triazoles from 4-...

Full description

Saved in:
Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2007-07, Vol.12 (8), p.1596-1605
Main Authors: Jin, Jian-yu, Zhang, Li-xue, Zhang, An-jiang, Lei, Xin-Xiang, Zhu, Jiang-Hai
Format: Article
Language:English
Subjects:
4-(arylmethylidene)amino-5-(D-galactopentitol-1-yl)-3-mercapto-4H-1
4-b]-1
4-thiadiazine
4-triazole
4-triazolo
Biological activity
Galactose
NMR
Plant growth
plant growth-regulating
Raphanus - drug effects
Raphanus - growth & development
Sugar Alcohols - pharmacology
Triazoles - chemical synthesis
Triazoles - chemistry
Triazoles - pharmacology
Triticum - drug effects
Triticum - growth & development
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To discover new 1,2,4-triazole derivatives which may possess significant biological activities, we synthesized a series of novel 6-aryl-3-(D-galactopentitol-1-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines and 4-(arylmethylidene)amino-5-(D-galactopentitol-1-yl)-3-mercapto-4H-1,2,4-triazoles from 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole. All the title compounds were characterized by elemental analysis, IR, 1H- and 13C-NMR. Plant growth-regulating activity tests showed that these compounds have remarkable effects on the growth of radish and wheat.
ISSN:1420-3049
1420-3049
DOI:10.3390/12081596