Disseminated Leishmaniasis Due to Using Immunosuppression Drugs: A Case Report

Visceral leishmaniasis is a common parasitic disease between humans and animals, transmitted by sandflies (Phlebotomus) in the Mediterranean countries, including Iran. The statistics have been reported less than real due to errors in the diagnosis and reporting of affected cases. In this report, we...

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Bibliographic Details
Published in:Iranian journal of parasitology 2020, Vol.15 (2), p.278-281
Main Authors: AFSHOON, Maryam, ABDOLSALEHI, Mohammadreza, ALINIA, Golnaz, BORHANI, Katayoun, YAGHMAIE, Bahareh, KHODABANDEH, Mahmoud
Format: Article
Language:English
Subjects:
Biopsy
Bone marrow
Case Report
Case reports
Immunosuppressive agents
Iran
Pancytopenia
Parasitic diseases
Splenomegaly
Visceral leishmaniasis
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Summary:Visceral leishmaniasis is a common parasitic disease between humans and animals, transmitted by sandflies (Phlebotomus) in the Mediterranean countries, including Iran. The statistics have been reported less than real due to errors in the diagnosis and reporting of affected cases. In this report, we will present the symptoms and manifestations of this disease to reduce late detection and exacerbating factors. The patient was a three-year-old girl from Tehran, Iran who had ascites and hepatomegaly. When she was 9 month-old, she was diagnosed as autoimmune hepatitis after liver biopsy and she was treated with immunosuppressive drugs (Azathioprine, prednisolone, and cyclosporine) for 22 months, but later she suffered from fever, pancytopenia, and hepatosplenomegaly. Then a bone marrow biopsy was done for her. There was a large amount of Leishman body in her bone marrow and treatment for Kala-azar was started for her. In patients with prolonged fever and splenomegaly, especially association with pancytopenia, consider leishmaniasis. Immunosuppressive drugs can disseminate parasitic diseases, including visceral leishmaniasis.
ISSN:1735-7020
2008-238X
DOI:10.18502/ijpa.v15i2.3312