Harnessing bioengineered microbes as a versatile platform for space nutrition

Human enterprises through the solar system will entail long-duration voyages and habitation creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory and nutritional attributes into microorganisms to develop customizable food production systems with minimal inputs,...

Full description

Saved in:
Bibliographic Details
Published in:Nature communications 2022-10, Vol.13 (1), p.6177-7, Article 6177
Main Authors: Llorente, Briardo, Williams, Thomas C., Goold, Hugh D., Pretorius, Isak S., Paulsen, Ian T.
Format: Article
Language:English
Subjects:
631/326/2522
631/61/318
631/61/338/552
Bioengineering
Carbon
Carbon dioxide
Diet
Ecosystem
Food
Food additives
Food production
Garbage collection
Humanities and Social Sciences
Humans
Mars
Metabolism
Microorganisms
multidisciplinary
Nutrients
Nutrition
Nutritional Status
Perspective
Science
Science (multidisciplinary)
Self sufficiency
Sensory properties
Space flight
Synthetic biology
Travel
Yeast
Yeasts
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03
cites cdi_FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03
container_end_page 7
container_issue 1
container_start_page 6177
container_title Nature communications
container_volume 13
creator Llorente, Briardo
Williams, Thomas C.
Goold, Hugh D.
Pretorius, Isak S.
Paulsen, Ian T.
description Human enterprises through the solar system will entail long-duration voyages and habitation creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory and nutritional attributes into microorganisms to develop customizable food production systems with minimal inputs, physical footprint, and waste. We envisage that a yeast collection bioengineered for one-carbon metabolism, optimal nutrition, and diverse textures, tastes, aromas, and colors could serve as a flexible food-production platform. Beyond its potential for supporting humans in space, bioengineered microbial-based food could lead to a new paradigm for Earth’s food manufacturing that provides greater self-sufficiency and removes pressure from natural ecosystems. Long-duration human space travel creates challenges for maintaining healthy diets. Here the authors discuss using synthetic biology approaches to modify yeast into an optimal, and enjoyable, food production platform.
doi_str_mv 10.1038/s41467-022-33974-7
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_2dbe2cba2b804ff28e25ef64f17a908f</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_2dbe2cba2b804ff28e25ef64f17a908f</doaj_id><sourcerecordid>2726154482</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03</originalsourceid><addsrcrecordid>eNp9kUFvFSEQxzdGY5tnv4AHs4kXL1thYGH3YmIatU1qvPROgB1WXnbhCbtN_PbFt21tPUgIEOY_P5j5V9VbSs4pYd3HzCkXsiEADWO95I18UZ0C4bShEtjLJ-eT6iznPSmD9bTj_HV1wgSIki5Oq--XOgXM2YexNj5iGH1ATDjUs7cpGsy1LrO-xZT14iesD5NeXExzXZY6H7TFOqxL8ouP4U31yukp49n9vqtuvn65ubhsrn98u7r4fN3YlpOlkUR0XFCDwmrWsvJRaVoj0IEZgPKBgXQDEW2Pshv6AQYrNaB2HTBiLWG76mrDDlHv1SH5WaffKmqvjhcxjUqnxdsJFQwGwRoNpiPcOegQWnSCOyp1TzpXWJ821mE1Mw4Ww5L09Az6PBL8TzXGW9W3HRBKC-DDPSDFXyvmRc0-W5wmHTCuWYEE0QNwyYv0_T_SfVxTKJ06qmjLeSlxV8GmKv3POaF7_Awl6o_3avNeFe_V0XslS9K7p2U8pjw4XQRsE-QSCiOmv2__B3sHLQS6vw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2726154482</pqid></control><display><type>article</type><title>Harnessing bioengineered microbes as a versatile platform for space nutrition</title><source>Nature（周刊和系列研究月刊）</source><source>Publicly Available Content Database</source><source>PubMed Central</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Llorente, Briardo ; Williams, Thomas C. ; Goold, Hugh D. ; Pretorius, Isak S. ; Paulsen, Ian T.</creator><creatorcontrib>Llorente, Briardo ; Williams, Thomas C. ; Goold, Hugh D. ; Pretorius, Isak S. ; Paulsen, Ian T.</creatorcontrib><description>Human enterprises through the solar system will entail long-duration voyages and habitation creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory and nutritional attributes into microorganisms to develop customizable food production systems with minimal inputs, physical footprint, and waste. We envisage that a yeast collection bioengineered for one-carbon metabolism, optimal nutrition, and diverse textures, tastes, aromas, and colors could serve as a flexible food-production platform. Beyond its potential for supporting humans in space, bioengineered microbial-based food could lead to a new paradigm for Earth’s food manufacturing that provides greater self-sufficiency and removes pressure from natural ecosystems. Long-duration human space travel creates challenges for maintaining healthy diets. Here the authors discuss using synthetic biology approaches to modify yeast into an optimal, and enjoyable, food production platform.</description><identifier>ISSN: 2041-1723</identifier><identifier>EISSN: 2041-1723</identifier><identifier>DOI: 10.1038/s41467-022-33974-7</identifier><identifier>PMID: 36261466</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/326/2522 ; 631/61/318 ; 631/61/338/552 ; Bioengineering ; Carbon ; Carbon dioxide ; Diet ; Ecosystem ; Food ; Food additives ; Food production ; Garbage collection ; Humanities and Social Sciences ; Humans ; Mars ; Metabolism ; Microorganisms ; multidisciplinary ; Nutrients ; Nutrition ; Nutritional Status ; Perspective ; Science ; Science (multidisciplinary) ; Self sufficiency ; Sensory properties ; Space flight ; Synthetic biology ; Travel ; Yeast ; Yeasts</subject><ispartof>Nature communications, 2022-10, Vol.13 (1), p.6177-7, Article 6177</ispartof><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03</citedby><cites>FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03</cites><orcidid>0000-0001-9015-9418 ; 0000-0002-0594-3441 ; 0000-0001-9127-3175 ; 0000-0002-3727-1395 ; 0000-0003-2888-3549</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2726154482/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2726154482?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25752,27923,27924,37011,37012,44589,53790,53792,74897</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36261466$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Llorente, Briardo</creatorcontrib><creatorcontrib>Williams, Thomas C.</creatorcontrib><creatorcontrib>Goold, Hugh D.</creatorcontrib><creatorcontrib>Pretorius, Isak S.</creatorcontrib><creatorcontrib>Paulsen, Ian T.</creatorcontrib><title>Harnessing bioengineered microbes as a versatile platform for space nutrition</title><title>Nature communications</title><addtitle>Nat Commun</addtitle><addtitle>Nat Commun</addtitle><description>Human enterprises through the solar system will entail long-duration voyages and habitation creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory and nutritional attributes into microorganisms to develop customizable food production systems with minimal inputs, physical footprint, and waste. We envisage that a yeast collection bioengineered for one-carbon metabolism, optimal nutrition, and diverse textures, tastes, aromas, and colors could serve as a flexible food-production platform. Beyond its potential for supporting humans in space, bioengineered microbial-based food could lead to a new paradigm for Earth’s food manufacturing that provides greater self-sufficiency and removes pressure from natural ecosystems. Long-duration human space travel creates challenges for maintaining healthy diets. Here the authors discuss using synthetic biology approaches to modify yeast into an optimal, and enjoyable, food production platform.</description><subject>631/326/2522</subject><subject>631/61/318</subject><subject>631/61/338/552</subject><subject>Bioengineering</subject><subject>Carbon</subject><subject>Carbon dioxide</subject><subject>Diet</subject><subject>Ecosystem</subject><subject>Food</subject><subject>Food additives</subject><subject>Food production</subject><subject>Garbage collection</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Mars</subject><subject>Metabolism</subject><subject>Microorganisms</subject><subject>multidisciplinary</subject><subject>Nutrients</subject><subject>Nutrition</subject><subject>Nutritional Status</subject><subject>Perspective</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Self sufficiency</subject><subject>Sensory properties</subject><subject>Space flight</subject><subject>Synthetic biology</subject><subject>Travel</subject><subject>Yeast</subject><subject>Yeasts</subject><issn>2041-1723</issn><issn>2041-1723</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9kUFvFSEQxzdGY5tnv4AHs4kXL1thYGH3YmIatU1qvPROgB1WXnbhCbtN_PbFt21tPUgIEOY_P5j5V9VbSs4pYd3HzCkXsiEADWO95I18UZ0C4bShEtjLJ-eT6iznPSmD9bTj_HV1wgSIki5Oq--XOgXM2YexNj5iGH1ATDjUs7cpGsy1LrO-xZT14iesD5NeXExzXZY6H7TFOqxL8ouP4U31yukp49n9vqtuvn65ubhsrn98u7r4fN3YlpOlkUR0XFCDwmrWsvJRaVoj0IEZgPKBgXQDEW2Pshv6AQYrNaB2HTBiLWG76mrDDlHv1SH5WaffKmqvjhcxjUqnxdsJFQwGwRoNpiPcOegQWnSCOyp1TzpXWJ821mE1Mw4Ww5L09Az6PBL8TzXGW9W3HRBKC-DDPSDFXyvmRc0-W5wmHTCuWYEE0QNwyYv0_T_SfVxTKJ06qmjLeSlxV8GmKv3POaF7_Awl6o_3avNeFe_V0XslS9K7p2U8pjw4XQRsE-QSCiOmv2__B3sHLQS6vw</recordid><startdate>20221019</startdate><enddate>20221019</enddate><creator>Llorente, Briardo</creator><creator>Williams, Thomas C.</creator><creator>Goold, Hugh D.</creator><creator>Pretorius, Isak S.</creator><creator>Paulsen, Ian T.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><general>Nature Portfolio</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SN</scope><scope>7SS</scope><scope>7ST</scope><scope>7T5</scope><scope>7T7</scope><scope>7TM</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>SOI</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-9015-9418</orcidid><orcidid>https://orcid.org/0000-0002-0594-3441</orcidid><orcidid>https://orcid.org/0000-0001-9127-3175</orcidid><orcidid>https://orcid.org/0000-0002-3727-1395</orcidid><orcidid>https://orcid.org/0000-0003-2888-3549</orcidid></search><sort><creationdate>20221019</creationdate><title>Harnessing bioengineered microbes as a versatile platform for space nutrition</title><author>Llorente, Briardo ; Williams, Thomas C. ; Goold, Hugh D. ; Pretorius, Isak S. ; Paulsen, Ian T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>631/326/2522</topic><topic>631/61/318</topic><topic>631/61/338/552</topic><topic>Bioengineering</topic><topic>Carbon</topic><topic>Carbon dioxide</topic><topic>Diet</topic><topic>Ecosystem</topic><topic>Food</topic><topic>Food additives</topic><topic>Food production</topic><topic>Garbage collection</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Mars</topic><topic>Metabolism</topic><topic>Microorganisms</topic><topic>multidisciplinary</topic><topic>Nutrients</topic><topic>Nutrition</topic><topic>Nutritional Status</topic><topic>Perspective</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Self sufficiency</topic><topic>Sensory properties</topic><topic>Space flight</topic><topic>Synthetic biology</topic><topic>Travel</topic><topic>Yeast</topic><topic>Yeasts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Llorente, Briardo</creatorcontrib><creatorcontrib>Williams, Thomas C.</creatorcontrib><creatorcontrib>Goold, Hugh D.</creatorcontrib><creatorcontrib>Pretorius, Isak S.</creatorcontrib><creatorcontrib>Paulsen, Ian T.</creatorcontrib><collection>SpringerOpen (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Open Access Journals</collection><jtitle>Nature communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Llorente, Briardo</au><au>Williams, Thomas C.</au><au>Goold, Hugh D.</au><au>Pretorius, Isak S.</au><au>Paulsen, Ian T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Harnessing bioengineered microbes as a versatile platform for space nutrition</atitle><jtitle>Nature communications</jtitle><stitle>Nat Commun</stitle><addtitle>Nat Commun</addtitle><date>2022-10-19</date><risdate>2022</risdate><volume>13</volume><issue>1</issue><spage>6177</spage><epage>7</epage><pages>6177-7</pages><artnum>6177</artnum><issn>2041-1723</issn><eissn>2041-1723</eissn><abstract>Human enterprises through the solar system will entail long-duration voyages and habitation creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory and nutritional attributes into microorganisms to develop customizable food production systems with minimal inputs, physical footprint, and waste. We envisage that a yeast collection bioengineered for one-carbon metabolism, optimal nutrition, and diverse textures, tastes, aromas, and colors could serve as a flexible food-production platform. Beyond its potential for supporting humans in space, bioengineered microbial-based food could lead to a new paradigm for Earth’s food manufacturing that provides greater self-sufficiency and removes pressure from natural ecosystems. Long-duration human space travel creates challenges for maintaining healthy diets. Here the authors discuss using synthetic biology approaches to modify yeast into an optimal, and enjoyable, food production platform.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>36261466</pmid><doi>10.1038/s41467-022-33974-7</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-9015-9418</orcidid><orcidid>https://orcid.org/0000-0002-0594-3441</orcidid><orcidid>https://orcid.org/0000-0001-9127-3175</orcidid><orcidid>https://orcid.org/0000-0002-3727-1395</orcidid><orcidid>https://orcid.org/0000-0003-2888-3549</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2041-1723
ispartof Nature communications, 2022-10, Vol.13 (1), p.6177-7, Article 6177
issn 2041-1723
2041-1723
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_2dbe2cba2b804ff28e25ef64f17a908f
source Nature（周刊和系列研究月刊）; Publicly Available Content Database; PubMed Central; Springer Nature - nature.com Journals - Fully Open Access
subjects 631/326/2522
631/61/318
631/61/338/552
Bioengineering
Carbon
Carbon dioxide
Diet
Ecosystem
Food
Food additives
Food production
Garbage collection
Humanities and Social Sciences
Humans
Mars
Metabolism
Microorganisms
multidisciplinary
Nutrients
Nutrition
Nutritional Status
Perspective
Science
Science (multidisciplinary)
Self sufficiency
Sensory properties
Space flight
Synthetic biology
Travel
Yeast
Yeasts
title Harnessing bioengineered microbes as a versatile platform for space nutrition
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T03%3A56%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Harnessing%20bioengineered%20microbes%20as%20a%20versatile%20platform%20for%20space%20nutrition&rft.jtitle=Nature%20communications&rft.au=Llorente,%20Briardo&rft.date=2022-10-19&rft.volume=13&rft.issue=1&rft.spage=6177&rft.epage=7&rft.pages=6177-7&rft.artnum=6177&rft.issn=2041-1723&rft.eissn=2041-1723&rft_id=info:doi/10.1038/s41467-022-33974-7&rft_dat=%3Cproquest_doaj_%3E2726154482%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c540t-7068461be6ca3530417b5b6ef2bd214d327fd0659e78d9d2dc7a2eaf8230cc03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2726154482&rft_id=info:pmid/36261466&rfr_iscdi=true