Bone Mineral Density and Vitamin D Values in Behçet’s Disease

• Published in: Turkish journal of osteoporosis 2018-12, Vol.24 (3), p.78-83
• Main Authors: Kul, Ayhan, Erdal, Akın
• Format: Article
• Language: English
• Subjects: 25-hydroxy vitamin D; Age; Arthritis; Behçet’s disease; Bone density; bone mineral density; Cytokines; Disease; Laboratories; Lead; Metabolism; Multiple sclerosis; Osteoporosis; Pathogenesis; Rheumatology; Tıp; Tumor necrosis factor-TNF; Vein & artery diseases; Vitamin D; Vitamin deficiency
• ISSN: 2146-3816; 2147-2653; 2147-2653
• DOI: 10.4274/tod.galenos.2018.16362

Objective: It was aim to compare the bone mineral density (BMD) and 25-hydroxy vitamin D (25-OH vitamin D) values of the patients with Behçet’s disease (BD) according to healthy population. Materials and Methods: A total of 34 patients diagnosed with BD which was 15 males and 19 females (mean age: 35.1±8.6 years; age range: 19 to 50 years), and 29 controls which was 12 males and 17 females (mean age: 36.9±9.2 years; age range: 21 to 51 years) were included in the study. The lumbar spine (L1-L4 total) measurements were made for the axial skeleton BMD values, and femur total and femur neck measurements were used for the appendicular skeleton BMD values. Results: The patients’ lumbar BMD values were significantly (p0.05). There was no significant correlation between the 25-OH vitamin D values and the BMD values of the groups (p>0.05). Conclusion: Even though the BD has a subclinical inflammatory course, it can cause a reduction of BMD by affecting the bone metabolism. Thus, the patients’ BMD values should be followed up, and when required vitamin D supplements should be administered to prevent the development of secondary osteoporosis.