Drug-resistant pandemic (H1N1) 2009, South Korea

Eleven patients with drug-resistant pandemic (H1N1) 2009 were identified in South Korea during May 2009-January 2010. Virus isolates from all patients had the H275Y mutation in the neuraminidase gene. One isolate had the I117M mutation. Of the 11 patients, 6 were ≥ 59 months of age, and 5 had underl...

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Bibliographic Details
Published in:Emerging infectious diseases 2011-04, Vol.17 (4), p.702-704
Main Authors: Shin, Soo Youn, Kang, Chun, Gwack, Jin, Kim, Joon Hyung, Kim, Hyun Su, Kang, Young A, Lee, Ha Gyung, Kim, Jin Seok, Lee, Jong Koo, Kim, Sung Han
Format: Article
Language:English
Subjects:
Adolescent
Adult
antimicrobial resistance
Antiviral Agents - pharmacology
Antiviral Agents - therapeutic use
antiviral drugs
Care and treatment
Child
Child, Preschool
Drug resistance
Drug Resistance, Viral - genetics
Epidemics
Female
Health aspects
Humans
Infant
influenza
Influenza A Virus, H1N1 Subtype - drug effects
Influenza A Virus, H1N1 Subtype - genetics
Influenza, Human - complications
Influenza, Human - drug therapy
Influenza, Human - mortality
Male
Medical research
Medicine, Experimental
Middle Aged
Mutation - genetics
oseltamivir
Oseltamivir - pharmacology
Oseltamivir - therapeutic use
Pandemic (H1N1) 2009 virus
Republic of Korea
South Korea
Treatment Outcome
Viral Proteins - genetics
viruses
Young Adult
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Description
Summary:Eleven patients with drug-resistant pandemic (H1N1) 2009 were identified in South Korea during May 2009-January 2010. Virus isolates from all patients had the H275Y mutation in the neuraminidase gene. One isolate had the I117M mutation. Of the 11 patients, 6 were ≥ 59 months of age, and 5 had underlying immunosuppressive conditions.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1704.101467