Inflammatory and Oxidative Stress Responses to High-Carbohydrate and High-Fat Meals in Healthy Humans

The postprandial state is hypothesised to be proinflammatory and prooxidative, but the relative contributions of fat versus carbohydrate are unclear. Therefore, we examined inflammation and oxidative stress responses in serum and skeletal muscle before and after 1000 kcal meals, which were high in e...

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Bibliographic Details
Published in:Journal of nutrition and metabolism 2012-01, Vol.2012 (2012), p.1-8
Main Authors: Campbell, L. V., Heilbronn, L. K., Samocha-Bonet, D., Gregersen, S.
Format: Article
Language:English
Subjects:
Clinical Study
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Summary:The postprandial state is hypothesised to be proinflammatory and prooxidative, but the relative contributions of fat versus carbohydrate are unclear. Therefore, we examined inflammation and oxidative stress responses in serum and skeletal muscle before and after 1000 kcal meals, which were high in either fat or carbohydrate in 15 healthy individuals. Serum and muscle expression of IL6 was elevated 3 hours after each meal, independently of macronutrient composition (P
ISSN:2090-0724
2090-0732
DOI:10.1155/2012/238056