Heart failure biomarkers in revascularized patients with stable coronary heart disease as clinical outcome predictors

The aim of this study was to investigate serum levels of galectin-3 (Gal-3) and N-terminal pro-brain Natriuretic Peptide (NT-proBNP) in patients with stable obstructive coronary artery disease, as well as their potential to predict clinical outcomes. This was a single-center cross-sectional cohort s...

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Published in:Frontiers in cardiovascular medicine 2024-09, Vol.11, p.1458120
Main Authors: Bošnjak, Ivica, Bedeković, Dražen, Selthofer-Relatić, Kristina, Roguljić, Hrvoje, Mihaljević, Ivica, Dukić, Darko, Bilić-Ćurčić, Ines
Format: Article
Language:English
Subjects:
biomarker
cardiac outcome
chronic coronary syndrome
coronary artery disease
galectin-3
NT-proBNP
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Summary:The aim of this study was to investigate serum levels of galectin-3 (Gal-3) and N-terminal pro-brain Natriuretic Peptide (NT-proBNP) in patients with stable obstructive coronary artery disease, as well as their potential to predict clinical outcomes. This was a single-center cross-sectional cohort study. 168 patients were divided into three groups: percutaneous coronary intervention (PCI) group (N 64), coronary artery bypass graft surgery (CABG) group (N 57), and group with no coronary stenosis (N 47). Gal-3 and NT-proBNP levels were measured and the Syntax score (Ss) was calculated. The mean value of Gal-3 was 19.98 ng/ml and 9.51 ng/ml (  
ISSN:2297-055X
2297-055X
DOI:10.3389/fcvm.2024.1458120