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Low-intensity continuous ultrasound to inhibit cancer cell migration
In recent years, it has been verified that collective cell migration is a fundamental step in tumor spreading and metastatic processes. In this paper, we demonstrate for the first time how low-intensity ultrasound produces long-term inhibition of collective migration of epithelial cancer cells in wo...
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Published in: | Frontiers in cell and developmental biology 2023-01, Vol.10, p.842965-842965 |
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Main Authors: | , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | In recent years, it has been verified that collective cell migration is a fundamental step in tumor spreading and metastatic processes. In this paper, we demonstrate for the first time how low-intensity ultrasound produces long-term inhibition of collective migration of epithelial cancer cells in wound healing processes. In particular, we show how pancreatic tumor cells, PANC-1, grown as monolayers
respond to these waves at frequencies close to 1 MHz and low intensities ( |
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ISSN: | 2296-634X 2296-634X |
DOI: | 10.3389/fcell.2022.842965 |