Genicunolide A, B and C: three new triterpenoids from Euphorbia geniculata

Three new triterpenoids, designated as genicunolide A (1), B (2) and C (3), along with friedelin (4) and friedelinol (5), were isolated from the aerial parts of Euphorbia geniculata. They were characterized as 1β-acetoxy-3β-hydroxy-11α,12α-oxidotaraxer-14-ene, 1β,3β-diacetoxy-21α-hydroxy-11α,12α-oxi...

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Bibliographic Details
Published in:Beilstein journal of organic chemistry 2015-12, Vol.11 (1), p.2707-2712
Main Authors: Farozi, Alia, Banday, Javid Ahmad, Shah, Shakeel Ahmad
Format: Article
Language:English
Subjects:
Chemistry
Euphorbia geniculata
Euphorbiaceae
friedelin
friedelinol
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genicunolide A
pentacyclic triterpenoids
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Summary:Three new triterpenoids, designated as genicunolide A (1), B (2) and C (3), along with friedelin (4) and friedelinol (5), were isolated from the aerial parts of Euphorbia geniculata. They were characterized as 1β-acetoxy-3β-hydroxy-11α,12α-oxidotaraxer-14-ene, 1β,3β-diacetoxy-21α-hydroxy-11α,12α-oxidotaraxer-14-ene and 3β,9α,20α-trihydroxy-Ψ-taraxast-5-ene, respectively, by spectral and chemical methods.
ISSN:1860-5397
2195-951X
1860-5397
DOI:10.3762/bjoc.11.291