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Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer
A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current...
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Published in: | Case reports in endocrinology 2017-01, Vol.2017 (2017), p.1-3 |
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creator | Kotani, Kohei Yoshida, Atsushi Sougawa, Mitsuharu Higashiyama, Shigeaki Kawabe, Joji Shiomi, Susumu |
description | A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current metastasis was impossible. 131I-radioiodine therapy (RIT) with 3.7 GBq 131I was not effective; therefore, stereotactic radiation therapy (SRT) using a CyberKnife radiotherapy system was scheduled. The prescription dose was 21 Gy, and a dose covering 95% of the planning target volume (PTV) in three fractions was administered. The PTV was 4,790 mm3. Follow-up magnetic resonance imaging conducted 3 and 12 months after the SRT demonstrated a remarkable and gradual reduction of the recurrent lymph node metastasis in the right parapharyngeal space and no evidence of recurrence. For multidisciplinary therapy of unresectable and/or RIT unresponsive locoregional lymph node metastases and recurrences of DTC, SRT using the CyberKnife system should be considered. |
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She had already undergone total thyroidectomy, five resections for cervical lymph node metastases, and right carotid rebuilding. Surgical resection of the current metastasis was impossible. 131I-radioiodine therapy (RIT) with 3.7 GBq 131I was not effective; therefore, stereotactic radiation therapy (SRT) using a CyberKnife radiotherapy system was scheduled. The prescription dose was 21 Gy, and a dose covering 95% of the planning target volume (PTV) in three fractions was administered. The PTV was 4,790 mm3. Follow-up magnetic resonance imaging conducted 3 and 12 months after the SRT demonstrated a remarkable and gradual reduction of the recurrent lymph node metastasis in the right parapharyngeal space and no evidence of recurrence. For multidisciplinary therapy of unresectable and/or RIT unresponsive locoregional lymph node metastases and recurrences of DTC, SRT using the CyberKnife system should be considered.</description><identifier>ISSN: 2090-6501</identifier><identifier>EISSN: 2090-651X</identifier><identifier>DOI: 10.1155/2017/7956726</identifier><identifier>PMID: 28396808</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Care and treatment ; Case Report ; Case studies ; Complications and side effects ; Development and progression ; Lymphatic diseases ; Metastasis ; Thyroid cancer</subject><ispartof>Case reports in endocrinology, 2017-01, Vol.2017 (2017), p.1-3</ispartof><rights>Copyright © 2017 Joji Kawabe et al.</rights><rights>COPYRIGHT 2017 John Wiley & Sons, Inc.</rights><rights>Copyright © 2017 Joji Kawabe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2017 Joji Kawabe et al. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-f8006780518950f1340587df2a1adc872d746cc4f8889752683166fafb05517c3</citedby><cites>FETCH-LOGICAL-c501t-f8006780518950f1340587df2a1adc872d746cc4f8889752683166fafb05517c3</cites><orcidid>0000-0002-4035-4984 ; 0000-0002-4828-743X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1881120659/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1881120659?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28396808$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Grüning, Thomas</contributor><creatorcontrib>Kotani, Kohei</creatorcontrib><creatorcontrib>Yoshida, Atsushi</creatorcontrib><creatorcontrib>Sougawa, Mitsuharu</creatorcontrib><creatorcontrib>Higashiyama, Shigeaki</creatorcontrib><creatorcontrib>Kawabe, Joji</creatorcontrib><creatorcontrib>Shiomi, Susumu</creatorcontrib><title>Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer</title><title>Case reports in endocrinology</title><addtitle>Case Rep Endocrinol</addtitle><description>A woman in her 60s presented with a recurrent lymph node metastasis from a papillary thyroid carcinoma in the right parapharyngeal space. 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For multidisciplinary therapy of unresectable and/or RIT unresponsive locoregional lymph node metastases and recurrences of DTC, SRT using the CyberKnife system should be considered.</description><subject>Care and treatment</subject><subject>Case Report</subject><subject>Case studies</subject><subject>Complications and side effects</subject><subject>Development and progression</subject><subject>Lymphatic diseases</subject><subject>Metastasis</subject><subject>Thyroid cancer</subject><issn>2090-6501</issn><issn>2090-651X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNks-LEzEUxwdR3KXuzbMEPGp3k8zkx1yEpbq6WBXWLXgLafLSpnQm3WTGZQ7-76bb2rXgwSSQ8PJ5X75feEXxkuBzQhi7oJiIC1EzLih_UpxSXOMxZ-TH08Mbk5PiLKUVzotjWpbV8-KEyrLmEsvT4tcsgevXLaSEgkPfO4gQOm06b9CNtj50S4h6M6BZ8u0CTYY5xM-td4BciOgGTB8jtB2aDs1mib4GC-gLdDrl4x8U33vnYIt43YFFt8shBm_RRLcG4ovimdPrBGf7e1TMrj7cTj6Np98-Xk8up2OT_XdjJ7N3ITEjsmbYkbLCTArrqCbaGimoFRU3pnJSylowymVJOHfazTFjRJhyVFzvdG3QK7WJvtFxUEF79VAIcaF0zJHXoKgjFDAYUQtecUYlEFvXsuQGV1aYedZ6t9Pa9PMGrMnRol4fiR7_tH6pFuGnYqXAVbY2Kl7vBWK46yF1ahX62Ob8ikhJCMWc1Y_UQmdXvnUhi5nGJ6MuGcNVTQllmTr_B5W3hcab0ILzuX7U8HbXYGJIKYI7GCdYbUdKbUdK7Ucq46_-DnuA_wxQBt7sgKVvrb73_ykHmQGnH2lSMcJE-RtFudwN</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Kotani, Kohei</creator><creator>Yoshida, Atsushi</creator><creator>Sougawa, Mitsuharu</creator><creator>Higashiyama, Shigeaki</creator><creator>Kawabe, Joji</creator><creator>Shiomi, Susumu</creator><general>Hindawi Publishing Corporation</general><general>Hindawi</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-4035-4984</orcidid><orcidid>https://orcid.org/0000-0002-4828-743X</orcidid></search><sort><creationdate>20170101</creationdate><title>Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer</title><author>Kotani, Kohei ; 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subjects | Care and treatment Case Report Case studies Complications and side effects Development and progression Lymphatic diseases Metastasis Thyroid cancer |
title | Usefulness of Stereotactic Radiotherapy Using CyberKnife for Recurrent Lymph Node Metastasis of Differentiated Thyroid Cancer |
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