Association of asthma with low serum vitamin D and its related musculoskeletal and psychological symptoms in adults: a case-control study

There are complex potential inter-relationships between the chronic inflammation of asthma and poor control, vitamin D deficiency, musculoskeletal pain and anxiety and depression. The aim was to investigate associations between vitamin D and these possible co-morbidities. This case-controlled study...

Full description

Saved in:
Bibliographic Details
Published in:NPJ primary care respiratory medicine 2021-05, Vol.31 (1), p.27-27, Article 27
Main Authors: Alkhatatbeh, Mohammad J., Almomani, Haneen S., Abdul-Razzak, Khalid K., Samrah, Shaher
Format: Article
Language:English
Subjects:
692/308/174
692/699/1785/31
Adult
Anxiety
Anxiety - epidemiology
Asthma
Asthma - epidemiology
Case-Control Studies
Humans
Internal Medicine
Medicine
Medicine & Public Health
Pain
Pneumology/Respiratory System
Primary Care Medicine
Thoracic Surgery
Vitamin D
Vitamin D Deficiency - complications
Vitamin D Deficiency - epidemiology
Vitamin deficiency
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There are complex potential inter-relationships between the chronic inflammation of asthma and poor control, vitamin D deficiency, musculoskeletal pain and anxiety and depression. The aim was to investigate associations between vitamin D and these possible co-morbidities. This case-controlled study involved 75 adults with asthma and 75 controls. Serum 25-hydroxyvitamin D (25(OH)D) was measured, levels of anxiety, depression, musculoskeletal pain, and asthma control were assessed. Participants with asthma had lower 25(OH)D and higher anxiety scores and higher measures of musculoskeletal pain compared to controls. Binary logistic regression showed that asthma was associated with decreased 25(OH)D (Odds ratio (OR) = 0.86), general weakness (OR = 13.29), complaint of musculoskeletal pain (OR = 13.73), and increased intensity of musculoskeletal pain (OR = 0.61) and number of painful sites (OR = 2.58). Asthma was not associated with anxiety or depression. Further studies are required to investigate if vitamin D supplementation can improve asthma symptoms and musculoskeletal pain.
ISSN:2055-1010
2055-1010
DOI:10.1038/s41533-021-00239-7