Feasibility of diffusion weighted magnetic resonance imaging in evaluation of different small bowel pathology

• Published in: Egyptian journal of radiology and nuclear medicine 2015-12, Vol.46 (4), p.859-869
• Main Authors: Afifi, A.H., Aboal Ela, A.M., Albanna, A.
• Format: Article
• Language: English
• Subjects: Bowel; Diffusion; Lymphoma; MRI
• ISSN: 0378-603X
• DOI: 10.1016/j.ejrnm.2015.08.017

Increasing capability of MR imaging via applying DWI gives additional information about the functional state of tissues with high potentials due to lacking radiation exposure and contrast hazards. Application included evaluation of gastrointestinal tumors and follow-up to assess response to treatment. In IBD, DWI is useful in highlighting bowel segments of active disease and the purpose of this study is to evaluate role of DWI-MRI in neoplastic and inflammatory small bowel diseases. Prospective study included 50 patients subjected to MRI enterography using 1.5T closed magnet followed with DWI and then ADC values were estimated. Ileo-colonoscopy and biopsy were done and pathological data were reviewed. Twenty-four males and 26 females with small bowel lesions were divided into two groups, 26 neoplastic (5 benign, 21 malignant) and 24 inflammatory lesions (48%). Mean ADC value of inflamed bowel was 1.59±0.45×10–3mm2/s, compared to 2.74±0.68×10–3mm2/s in normal bowel. ADC value of neoplastic lesions ranged from 0.6 to 1.5 and non-neoplastic lesions from 1.1 to 2. ADC value of lymphoma ranged from 0.6 to 0.7×10–3mm2/s and adenocarcinomas from 0.8 to 1.0×10–3mm2/s. DWI is an important complementary sequence with the routine MRI of the small bowel helping in lesion characterization and differentiation of pathology.