Gender-Dependent Association Between Thyroid Hormones and Severity of Coronary Artery Disease by SYNTAX Score

Thyroid function has been shown to be associated with cardiovascular diseases. Moreover, sex can influence on the association between thyroid function and other diseases. We aimed to evaluate the relationship between thyroid hormones and the severity of coronary artery disease (CAD) and outcomes. In...

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Bibliographic Details
Published in:Acta medica Iranica 2024-11, Vol.62 (1)
Main Authors: Eskandari, Ramin, Vatandoost, Mona, Nourian, Saeid, Rezaei, Yousef
Format: Article
Language:English
Subjects:
Coronary artery disease
Prognosis
Sex
SYNTAX score
Thyroid hormone
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Summary:Thyroid function has been shown to be associated with cardiovascular diseases. Moreover, sex can influence on the association between thyroid function and other diseases. We aimed to evaluate the relationship between thyroid hormones and the severity of coronary artery disease (CAD) and outcomes. In a prospective study, patients with chest pain undergoing diagnostic coronary angiography were evaluated. Patients were categorized based on the number of involved coronary arteries. Moreover, the severity of CAD was quantitatively calculated using the Syntax score (SS). All patients were also followed up for 3-month duration. The level of TSH in 150 patients was significantly higher in females than males (3.1 [1.7, 5] versus 1.8 [1, 3.3] mU/L; P=0.002). There was significant correlation between THS and the SS among females (ρ=0.477, P
ISSN:0044-6025
1735-9694
DOI:10.18502/acta.v62i1.16883