Antidiabetic and Anti-hyperlipidemic Effects of the Crude Hydromethanol Extract of Hagenia abyssinica (Rosaceae) Leaves in Streptozotocin-Induced Diabetic Mice

The leaves of (Rosaceae) have been used traditionally for the management of diabetes mellitus. Thus, this study aimed to evaluate the antidiabetic and anti-hyperlipidemic activity of leaves crude extract in streptozotocin-induced diabetic mice. Antidiabetic and anti-hyperlipidemic activity of the cr...

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Bibliographic Details
Published in:Diabetes, metabolic syndrome and obesity metabolic syndrome and obesity, 2020-01, Vol.13, p.4085-4094
Main Authors: Kifle, Zemene Demelash, Belayneh, Yaschilal Muche
Format: Article
Language:English
Subjects:
Albinism
Analysis
Anticholesteremic agents
Antidiabetics
Blood cholesterol
Blood glucose
Body weight
Chloride
Diabetes
Diabetes mellitus
Diabetes therapy
Drugs
Experiments
Flavonoids
Flowers & plants
Glucose
hagenia abyssinica
Herbal medicine
Insulin
Laboratory animals
Low density lipoproteins
Medical research
Metabolism
Metabolites
Original Research
Phytochemicals
Solvents
Streptozocin
streptozotocin
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Summary:The leaves of (Rosaceae) have been used traditionally for the management of diabetes mellitus. Thus, this study aimed to evaluate the antidiabetic and anti-hyperlipidemic activity of leaves crude extract in streptozotocin-induced diabetic mice. Antidiabetic and anti-hyperlipidemic activity of the crude extract of was studied in streptozotocin-induced diabetic mice. The effects of the extract on fasting blood glucose level, body weight, and serum lipid profiles were analyzed. One-way ANOVA followed by Tukey's post hoc test was used for data analysis and p
ISSN:1178-7007
1178-7007
DOI:10.2147/DMSO.S279475