Study of the Effects of Wall Thickness and Size Variations on the Rupture Risk of Cerebral Aneurysms Using FSI Simulations

Cerebral aneurysms come in a wide range of shapes and sizes; they can also evolve over time, presenting significant changes. Large aneurysms are generally thought to be more prone to rupture, but rupture has also been observed in small aneurysms, indicating the presence of additional risk factors. T...

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Bibliographic Details
Published in:Applied sciences 2024-08, Vol.14 (15), p.6717
Main Authors: Díaz, Daniel, Valencia, Álvaro
Format: Article
Language:English
Subjects:
Algorithms
aneurysm removal
Aneurysms
Approximation
cerebral aneurysms
Fluid dynamics
FSI
Hemodynamics
Hypertension
Medical imaging
Medical research
Medicine, Experimental
Risk factors
Simulation
Simulation methods
simulations
size
Veins & arteries
wall thickness
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Summary:Cerebral aneurysms come in a wide range of shapes and sizes; they can also evolve over time, presenting significant changes. Large aneurysms are generally thought to be more prone to rupture, but rupture has also been observed in small aneurysms, indicating the presence of additional risk factors. The aim of this study was to assess the effects of the aneurysm’s size and wall thickness on its rupture risk, by using fluid–structure interaction simulations. Six patient-specific geometries were studied: four related to the effect of size and two related to the effect of wall thickness. Additional cases in which the aneurysm was removed were included. It was found that thinner walls suffered from significantly greater stresses, whereas an increment in size led, in general, to lower levels of wall shear stress and greater equivalent stress. By removing the aneurysm, the reduction in the time-averaged wall shear stress was 75% at the rupture point. Although the size of an aneurysm has a great impact on its rupture risk, the wall thickness needs to be considered, since with maintenance of its size, an aneurysm can suffer from wall thinning, which can lead to structural failure.
ISSN:2076-3417
2076-3417
DOI:10.3390/app14156717