A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach

Anthrax is caused by . Humans are mainly infected through contact with the fur and meat of livestock. The cutaneous form is the most common form. The skin lesions of typical cutaneous anthrax are characterized by shallow ulcers with black crusts, surrounded by small blisters and nonpitting edema of...

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Bibliographic Details
Published in:Infection and drug resistance 2023-06, Vol.16, p.3601-3606
Main Authors: Liu, Yushan, Zheng, Gezhi, Li, Jing, Yang, Nan, Li, Juan, Liu, Zhengwen, Han, Qunying, Zhao, Yingren, Du, Fenjing, He, Yingli, Yan, Taotao
Format: Article
Language:English
Subjects:
Anthrax
Case Report
cutaneous anthrax
Development and progression
etiology diagnosis
Livestock
metagenomic next-generation sequencing
mngs
Prognosis
Skin
Tazobactam
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Summary:Anthrax is caused by . Humans are mainly infected through contact with the fur and meat of livestock. The cutaneous form is the most common form. The skin lesions of typical cutaneous anthrax are characterized by shallow ulcers with black crusts, surrounded by small blisters and nonpitting edema of nearby tissues. Metagenomic next-generation sequencing (mNGS) is a new pathogenic detection method which is rapid and unbiased. We reported the first case of cutaneous anthrax diagnosed by mNGS. Ultimately, the man received prompt antibiotic therapy and had a good prognosis. In conclusion, mNGS is proved to be a good method for etiological diagnosis, especially for rare infectious diseases.
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S411717