Influence of indentation test factors on the mechanical response of the skin

This study proposes in vivo tests and design of experiments to determine the influence of experimental factors on the mechanical response of the soft tissue. The experimental factors considered are: room temperature (A), indentation velocity (B), indenter temperature (C), pump pressure (D) and muscl...

Full description

Saved in:
Bibliographic Details
Published in:Universitas scientiarum 2019-04, Vol.24 (1), p.49-72
Main Authors: Isaza, Jesica Andrea, Lacroix, Damien, Ramírez, Juan
Format: Article
Language:eng ; por
Subjects:
Biological models (mathematics)
Biomedical materials
Constants
Constitutive equations
Constitutive relationships
Design of experiments
Finite element method
finite element method
inverse analysis
constitutive equation
human skin
Hardness tests
Hypodermis
In vivo methods and tests
Indentation
Inverse method
Mathematical analysis
Mathematical models
Mechanical analysis
Mechanical properties
MULTIDISCIPLINARY SCIENCES
Multilayers
Muscle contraction
Muscles
Numerical models
Room temperature
Skin
Soft tissues
Statistical analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study proposes in vivo tests and design of experiments to determine the influence of experimental factors on the mechanical response of the soft tissue. The experimental factors considered are: room temperature (A), indentation velocity (B), indenter temperature (C), pump pressure (D) and muscle activation (E). An inverse method was developed to obtain the constants for constitutive equations of a multilayer biological model (skin, hypodermis, and muscle) through the use of indentation tests in combination with a finite element method. For each combination of the experimental factors, two groups of constants were established from the inverse method. Sixteen combinations of experimental conditions and their corresponding constants for the Mooney-Rivlin constitutive equations were obtained to be used in further numerical models. The factor D and factor interactions ADE, CDE, and ACDE were statistically significant with respect to skin mechanical response. Therefore, it can be concluded that there is not a current equation able to represent the mechanical properties of the skin under all the experimental conditions considered in this study.
ISSN:0122-7483
2027-1352
DOI:10.11144/Javeriana.SC24-1.ioit