Fractal analysis of left ventricular trabeculae in post-STEMI: from acute to chronic phase

• Published in: Insights into imaging 2024-03, Vol.15 (1), p.75-14, Article 75
• Main Authors: Shi, Ruo-Yang, Wu, Rui, Ran, Jinjun, Tang, Lang-Lang, Wesemann, Luke, Hu, Jiani, Du, Liang, Zhang, Wei-Jun, Xu, Jian-Rong, Zhou, Yan, Zhao, Lei, Pu, Jun, Wu, Lian-Ming
• Format: Article
• Language: English
• Subjects: Cine; Complexity; Correlation; Diagnostic Radiology; Fractal analysis; Fractal geometry; Fractals; Heart attacks; Heart rate; Imaging; Internal Medicine; Interventional Radiology; Magnetic resonance; Magnetic resonance imaging; Medicine; Medicine & Public Health; Myocardial infarction; Myocardium; Neuroradiology; Original; Original Article; Radiology; Remote regions; ST elevation myocardial infarction; Ultrasound
• ISSN: 1869-4101; 1869-4101
• DOI: 10.1186/s13244-024-01641-8

Purpose The temporal evolution of ventricular trabecular complexity and its correlation with major adverse cardiovascular events (MACE) remain indeterminate in patients presenting with acute ST elevation myocardial infarction (STEMI). Methods This retrospective analysis enrolled patients undergoing primary percutaneous coronary intervention (pPCI) for acute STEMI, possessing cardiac magnetic resonance (CMR) data in the acute (within 7 days), subacute (1 month after pPCI), and chronic phases (6 months after pPCI) from January 2015 to January 2020 at the three participating sites. Fractal dimensions (FD) were measured for the global, infarct, and remote regions of left ventricular trabeculae during each phase. The potential association of FD with MACE was analyzed using multivariate Cox regression. Results Among the 200 analyzed patients (182 men; median age, 61 years; age range, 50–66 years), 37 (18.5%) encountered MACE during a median follow-up of 31.2 months. FD exhibited a gradual decrement (global FD at acute, subacute, and chronic phases: 1.253 ± 0.049, 1.239 ± 0.046, 1.230 ± 0.045, p