EVALUATION OF PERIPAPILLARY RETINAL NERVE FIBRE LAYER AND CENTRAL MACULAR THICKNESS INADULTS WITH HYPEROPIC ANISOMETROPIC AMBLYOPIA

• Published in: Pakistan Armed Forces medical journal 2021-02, Vol.71 (1), p.162-66
• Main Authors: Ahmed, Tanveer, Niazi, Khizar, Shah, Sobia Usman, Khan, Junaid Afsar, Bukhsh, Husnain Muhammad, Ashraf, Muhammad Arslan
• Format: Article
• Language: English
• Subjects: Age; Amblyopia; Analysis; anisometropia; central macular thickness (cmt); Diabetic retinopathy; Diagnosis; Neurophysiology; optical coherence tomography (oct); Pathology; peri-papillary retinal nerve fibre layer (prnfl); Retina; Sample size; Strabismus; Vision disorders in children; Visual impairment
• ISSN: 0030-9648; 2411-8842
• DOI: 10.51253/pafmj.v71i1.3975

Objective: To study per-papillary retinal nerve fibre layer (pRNFL) and central macular thickness (CMT) changesin adults with hyperopic anisometropic amblyopia using optical coherence tomography. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital, Lahore, Pakistan, from Oct 2019 to Feb 2020. Methodology: In this study 30 adults, 18-40 years of age were included who presented in our clinic with monocular poor vision. They underwent detailed ophthalmic clinical examination: including corrected and uncorrected distance visual acuity, slit lamp bio-microscopy and fundus examination with 90 diopter lens. After fulfilling criteria of anisometropic amblyopia, central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness was measured by using RS-3000 SLO, NIDEK Co, Japan spectral domain optical coherence tomography device and compared the central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic and fellow eye of same individual. Results: The mean change in per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic eyes, 121.48± 4.90 μm and non amblyopic eyes was 112.92 ± 4.72 μm with statistical significance (p