Bone marrow oxalosis: An unusual cause of cytopenia in end-stage renal disease; report of two cases

Systemic oxalosis can be either primary or secondary hyperoxaluria. Oxalosis is a phenomenon in which calcium oxalate crystals deposit in various visceral organs leading to bone marrow (BM) failure and recurrent renal stones. We describe two rare cases of BM oxalosis. Hyperoxaluria is strongly assoc...

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Bibliographic Details
Published in:Indian journal of pathology & microbiology 2018-04, Vol.61 (2), p.268-270
Main Authors: Sharma, Seema, Rao, Ram, Pani, Krushna, Paul, Paramita
Format: Article
Language:English
Subjects:
Anemia
Biopsy
Bone marrow
Bone marrow diseases
Calcinosis
Calcium
Calcium oxalate
Calculi
Case studies
Crystals
Cytopenia
Diagnosis
End-stage renal disease
Enzymes
Hyperoxaluria
Kidney diseases
Kidney stones
Lithiasis
Lithotripsy
Liver
Metabolism
Microscopy
Nephrolithiasis
Nervous system
Organs
Oxalic acid
Oxalosis
pancytopenia
Patients
Renal failure
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Summary:Systemic oxalosis can be either primary or secondary hyperoxaluria. Oxalosis is a phenomenon in which calcium oxalate crystals deposit in various visceral organs leading to bone marrow (BM) failure and recurrent renal stones. We describe two rare cases of BM oxalosis. Hyperoxaluria is strongly associated with nephrolithiasis and nephrocalcinosis. Both the patients presented with recurrent renal stones and a variable degree of BM failure. BM oxalosis should be considered as a possible diagnosis in patients in recurrent nephrolithiasis and cytopenia.
ISSN:0377-4929
0974-5130
DOI:10.4103/IJPM.IJPM_572_17