Quantifying the effect of isoflurane and nitrous oxide on somatosensory-evoked potentials

Anaesthetic techniques may have a significant effect on intraoperative-evoked potentials (EP). The present study is designed to compare Propofol anaesthesia with Isoflurane (with or without nitrous oxide) during intraoperative somatosensory-evoked potential (SSEP) monitoring in 15 ASA Grade I and II...

Full description

Saved in:
Bibliographic Details
Published in:Indian journal of anaesthesia 2010-01, Vol.54 (1), p.40-44
Main Authors: Devadoss, Usha, Babu, S, Cherian, Vt
Format: Article
Language:English
Subjects:
Anesthesia
Anesthesiology
Brain tumour
Clinical Investigation
Comparative studies
Evoked potentials (Electrophysiology)
Health aspects
Isoflurane
monitoring
Nitrous oxide
Propofol
SSEP
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Anaesthetic techniques may have a significant effect on intraoperative-evoked potentials (EP). The present study is designed to compare Propofol anaesthesia with Isoflurane (with or without nitrous oxide) during intraoperative somatosensory-evoked potential (SSEP) monitoring in 15 ASA Grade I and II patients undergoing surgery for intracranial tumours. SSEPs in response to median and posterior tibial nerve stimulation were recorded under four different anaesthetic conditions: 1) Propofol infusion and ventilation with air-oxygen, 2) Isoflurane, 1.0 MAC and ventilation with air-oxygen, 3) Isoflurane 1.0 MAC and ventilation with nitrous oxide-oxygen, and 4) Return to Isoflurane, 1.0 MAC and ventilation with air-oxygen. Intraoperative monitoring of somatosensory evoked potentials is best recordable using Propofol. The morphology of the EP is reproducible with Isoflurane. This effect is exaggerated when it is advisable to avoid nitrous oxide.
ISSN:0019-5049
0976-2817
DOI:10.4103/0019-5049.60496