Predictive Role of Proteinuria in Urinary Tract Infection

• Published in: Journal of clinical and diagnostic research 2017-10, Vol.11 (10), p.DC01-DC03
• Main Authors: Bharara, Tanisha, Sharma, Abha, Gur, Renu, Duggal, Shalini Dewan, Jena, Pragnya Paramita, Kumar, Avinash
• Format: Article
• Language: English
• Subjects: Antimicrobial resistance; Pyuria; Urine albumin; Urine culture
• ISSN: 2249-782X; 0973-709X; 2249-782X
• DOI: 10.7860/JCDR/2017/29615.10720

Introduction: Urine culture is considered as holy grail in diagnosis of Urinary Tract Infection (UTI). However, the significance of preliminary urinalysis cannot be neglected. Aim: To evaluate proteinuria as a predictor of UTI. Materials and Methods: This study was conducted at the Department of Microbiology, Dr. Baba Saheb Ambedkar Hospital, New Delhi, India, over a period of three months (April 2015 to June 2015). Urine specimens from clinically suspected cases of UTI were analysed microscopically for pyuria and by reagent strip test for albuminuria. The results were correlated with urine culture findings. Antimicrobial resistance for various antimicrobials was compared among proteinuria positive and negative cases. Statistical analysis was done by Fisherfs-exact test and p-value was calculated. A p-value .0.05 was considered significant. Results: A total of 369 urine samples received for both routine microscopy and culture, out of which 73 were proteinuria positive. Out of these 73 samples, 32 were culture positive while 41 were culture negative. Among culture positive, 62.5% patients were symptomatic (20/32) while 37.5% were asymptomatic (12/32). Their age ranged from five months to 83 years. Male to female ratio was 1:1.5. Association between culture positivity and proteinuria was statistically significant (p