Efficacy of prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review meta-analysis

The susceptibility to surgical site occurrence (SSO) is high following ventral hernia repair (VHR) surgery. SSO severely increases the physical and mental burden on patients. The main purpose of this review was to analyze the efficacy of negative pressure wound therapy (NPWT) after open VHR(OVHR) an...

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Published in:BMC surgery 2023-12, Vol.23 (1), p.374-374, Article 374
Main Authors: Xu, Yang, Shao, Shuai, Gong, ZeZhong, Ri, HyokJu, Xu, ZhaoHui, Kang, HaoNan, Shan, Yan, Amadou, Boureima Hamidou, Ren, YanYing, Zhang, Fan, Chen, Xin
Format: Article
Language:English
Subjects:
Abdomen
Analysis
Bias
Clinical trials
Cohort analysis
Complications and side effects
Data collection
Dehiscence
Effectiveness
Hematoma
Hernia
Hernias
Infectious diseases
Medical research
Medicine, Experimental
Meta-analysis
Necrosis
NPWT
OVHR
Review
Skin
Software
Surgery
Surgical site infections
Surgical site occurrences
Systematic review
Ventral hernia
Wound dehiscence
Wound healing
Wounds
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Summary:The susceptibility to surgical site occurrence (SSO) is high following ventral hernia repair (VHR) surgery. SSO severely increases the physical and mental burden on patients. The main purpose of this review was to analyze the efficacy of negative pressure wound therapy (NPWT) after open VHR(OVHR) and explore benefits to patients. The Cochrane Library, PubMed, and Embase databases were searched from the date of establishment to 15 October 2022. All randomized controlled trials and retrospective cohort studies comparing NPWT with standard dressings after OVHR were included. The Revman 5.4 software recommended by Cochrane and the STATA16 software were used in this meta-analysis. Fifteen studies (involving 1666 patients) were identified and included in the meta-analysis, with 821 patients receiving NPWT. Overall, the incidence rate of SSO in the NPWT group was lower compared to the control group (odds ratio [OR] = 0.44; 95% confidence interval [CI] = 0.21-0.93; I  = 86%; P = 0.03). The occurrence rate of surgical site infection (SSI; OR = 0.51; 95% CI = 0.38-0.68, P 
ISSN:1471-2482
1471-2482
DOI:10.1186/s12893-023-02280-4