Infantile Myofibroma Eroding into the Frontal Bone : A Case Report and Review of Its Histopathologic Differential Diagnosis

Infantile myofibroma is a rare and benign tumour of children presenting in the head and neck region. Rendering a final diagnosis of infantile myofibroma can be challenging in the light of nonspecific clinical, radiological findings and its histopathological similarities with a number of neoplasms es...

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Bibliographic Details
Published in:Case reports in pediatrics 2012-01, Vol.2012 (2012), p.1-5
Main Authors: Thennavan, Aatish, Narayanaswamy, Venkadasalapathi, Niazi, Thanvir Mohammed, Rao, Lakshmi, Radhakrishnan, Raghu
Format: Article
Language:English
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Case Report
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Summary:Infantile myofibroma is a rare and benign tumour of children presenting in the head and neck region. Rendering a final diagnosis of infantile myofibroma can be challenging in the light of nonspecific clinical, radiological findings and its histopathological similarities with a number of neoplasms especially spindle cell tumours. In this paper we discuss a case of infantile myofibroma in a 2-month-old infant, enumerating the various differential entities that have to be eliminated in reaching its specific diagnosis and highlighting the importance of immunopositivity to vimentin and smooth muscle actin (SMA) in establishing its myofibroblastic differentiation.
ISSN:2090-6803
2090-6811
DOI:10.1155/2012/630804