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A Systematic Review and Meta-Analysis of Influenza A Virus Infection During Pregnancy Associated with an Increased Risk for Stillbirth and Low Birth Weight

Background/Aims: Impaired pregnancy outcomes, such as low birth weight are associated with increased disease risk in later life, however little is known about the impact of common infectious diseases during pregnancy on birth weight. The study had two aims: a) to investigate risk factors of influenz...

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Published in:Kidney & blood pressure research 2017-01, Vol.42 (2), p.232-243
Main Authors: He, Jing, Liu, Zhi-Wei, Lu, Yong-Ping, Li, Tao-Yuan, Liang, Xu-Jing, Arck, Petra C., Huang, Si-Min, Hocher, Berthold, Chen, You-Peng
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Language:English
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Summary:Background/Aims: Impaired pregnancy outcomes, such as low birth weight are associated with increased disease risk in later life, however little is known about the impact of common infectious diseases during pregnancy on birth weight. The study had two aims: a) to investigate risk factors of influenza virus infection during pregnancy, and b) to analyze the impact of influenza virus infection on pregnancy outcome, especially birth weight. Methods: Prospective and retrospective observational studies found in PubMed, MEDLINE, Embase, Google Scholar, and WangFang database were included in this meta analysis. Data of included studies was extracted and analyzed by the RevMan software. Results: Pregnant women with anemia (P=0.004, RR=1.46, 95% CI: 1.13-1.88), obesity (P
ISSN:1420-4096
1423-0143
DOI:10.1159/000477221