First description of gastroenteritis viruses in Lebanese children: A pilot study

Summary Human enteric viruses are important causes of acute gastroenteritis in infants and children. The role of rotaviruses, adenoviruses, human caliciviruses and astroviruses in the development of severe acute gastroenteritis requiring hospitalization of infants and young children in North Lebanon...

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Bibliographic Details
Published in:Journal of infection and public health 2011-06, Vol.4 (2), p.59-64
Main Authors: Al-Ali, Randa Meraabi, Chehadeh, Wassim, Hamze, Monzer, Dabboussi, Fouad, Hlais, Sani, Mallat, Hassan
Format: Article
Language:English
Subjects:
Adenovirus
Age Factors
Astrovirus
Child
Child, Preschool
Feces - virology
Female
Gastroenteritis
Gastroenteritis - epidemiology
Gastroenteritis - pathology
Gastroenteritis - virology
Hospitalization - statistics & numerical data
Humans
Immunoassay
Infant
Infectious Disease
Internal Medicine
Lebanon - epidemiology
Male
Norovirus
Pilot Projects
Polymerase Chain Reaction
Prevalence
Rotavirus
Sapovirus
Virus Diseases - epidemiology
Virus Diseases - pathology
Virus Diseases - virology
Viruses - classification
Viruses - isolation & purification
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Summary:Summary Human enteric viruses are important causes of acute gastroenteritis in infants and children. The role of rotaviruses, adenoviruses, human caliciviruses and astroviruses in the development of severe acute gastroenteritis requiring hospitalization of infants and young children in North Lebanon was investigated. Stool specimens collected between April and May 2010 from 79 Lebanese infants and children hospitalized for severe acute gastroenteritis, were screened for enteric viruses by immunoassays and internally controlled multiplex PCR assay. Out of 79 stool samples, 38 (48%) were positive for rotavirus, and 5 (6%) were positive for norovirus genogroup II. Enteric adenoviruses, sapoviruses and human astroviruses were not detected. Children with severe rotavirus gastroenteritis were younger than those with severe norovirus gastroenteritis. These results highlight the importance of rotavirus and norovirus as causes of severe gastroenteritis in Lebanese children, and the need to incorporate routine screening tests for norovirus infection in clinical settings.
ISSN:1876-0341
1876-035X
DOI:10.1016/j.jiph.2011.01.002