Adipose tissue stromal vascular fraction in the treatment of full thickness burns in rats

ABSTRACT PURPOSE: To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS: Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups receive...

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Bibliographic Details
Published in:Acta cirúrgica brasileira 2016-09, Vol.31 (9), p.578-585
Main Authors: Cardoso, Alexandre Lamaro, Bachion, Maria Márcia, Morais, Júlia de Miranda, Fantinati, Marcelo Silva, Almeida, Vera Lúcia Lima de, Lino Júnior, Ruy Souza
Format: Article
Language:English
Subjects:
Burns
Rats
Wound Healing
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Summary:ABSTRACT PURPOSE: To analyze the healing effects of stromal vascular fraction (SVF) application compared to wound dressing with 2% silver sulfadiazine in full thickness burn wounds in rats. METHODS: Animals were divided into two groups: 2% silver sulfadiazine group and SVF group. Both groups received occlusive bandages while the first one was treated with 2% silver sulfadiazine and the latter was treated with injections of SVF prepared from adipose tissue extracted from an animal donor. The animals were accompanied through 3, 7 and 30 days for evaluation of macroscopic, microscopic and morphometric aspects. RESULTS: On day three, a significant increase (p
ISSN:0102-8650
0102-8650
DOI:10.1590/S0102-865020160090000002