Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial

Background: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute eff...

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Bibliographic Details
Published in:Nutrients 2022-09, Vol.14 (18), p.3736
Main Authors: Moreira, Fernanda Duarte, Reis, Caio Eduardo Gonçalves, Welker, Alexis Fonseca, Gallassi, Andrea Donatti
Format: Article
Language:English
Subjects:
Acute effects
Bitterness
Blood Glucose
Blood sugar
Body composition
Carbohydrates
Clinical trials
complex carbohydrates
Control
Cross-Over Studies
Dapagliflozin
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2
Diabetes therapy
Diet therapy
Dietary fiber
Evaluation
Flax
Flaxseed
Glucose
Glycemic Index
Health aspects
Hemoglobin
Humans
Hyperglycemia
Immunoassay
Ingestion
Insulin
Insulin resistance
Lipids
Male
Olfaction
Palatability
postprandial blood glucose
Postprandial Period
Product development
Saltiness
Smell
Sourness
Sweetness
Taste
Type 2 diabetes
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Summary:Background: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute effects of raw flaxseed consumption on the 2 h postprandial glycemic curve in men with type 2 diabetes mellitus (T2DM). Methods: This was a randomized crossover clinical trial. Nineteen men with T2DM were randomly assigned a standardized breakfast without (control) or with a previous intake of 15 g of ground raw golden flaxseed (flax). Glycemia was measured at fasting and postprandial at 15, 30, 45, 60, 90, and 120 min. Palatability markers (visual appeal, smell, and pleasantness of taste) and taste intensity (sweetness, saltiness, bitterness, sourness, and creaminess) were evaluated. Results: The peak glucose rise and the 2 h AUC glycemic response reduced in the flax group by 17% (p = 0.001) and 24% (p < 0.001), respectively. The glucose peak time, palatability, and taste parameters did not differ between the two groups. Conclusions: Ingestion of 15 g of ground raw golden flaxseed before breakfast decreases the 2 h postprandial glycemic response in men with T2DM.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu14183736