Data set in support of neurotoxicity of trimethyltin chloride by morphological and protein analysis

Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neuro...

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Bibliographic Details
Published in:Data in brief 2016-03, Vol.6, p.706-709
Main Authors: Kim, C-Yoon, Kim, Jin, Song, Juha, Oh, Hanseul, Park, Jae-Hak
Format: Article
Language:English
Subjects:
Data
Neurotoxicity
Trimethyltin chloride
Zebrafish
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Summary:Trimethyltin chloride (TMT) is a neurotoxicant widely present in the aquatic environment. Chronic exposure of embryos to TMT for 4 days post-fertilization (dpf) elicited a concentration-related decrease in head & eye size and increase in axial malformation. In addition, Rohon-Beard sensory neurons and motor neurons showed decreased patterns of protein expression. These data coincide with previous research about the neurotoxicity of TMT on mRNA expression (Kim et al., 2016 [1]). These data demonstrates that TMT inhibits specific neurodevelopmental stages in zebrafish embryos and suggests a possible mechanism for the toxicity of TMT in vertebrate neurodevelopment. This paper contains data related to research concurrently published in Kim et al. (2016) [1].
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2016.01.021