Recurrent vincristine‐associated fever in a child with Wilms tumor

Background Fever is a common complaint among children with an underlying oncologic diagnosis, especially during chemotherapy courses and periods of neutropenia. Chemotherapy‐induced fever is well described in relation to specific chemotherapy agents. However, fever induced by vincristine (VCR) has o...

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Bibliographic Details
Published in:Cancer reports 2022-10, Vol.5 (10), p.n/a
Main Authors: Al‐Antary, Eman T., Ramiz, Sarah
Format: Article
Language:English
Subjects:
Abdomen
acetaminophen
Analgesics
Blood
Cancer therapies
Case Report
Case Reports
Chemotherapy
Children & youth
Conflicts of interest
dexamethasone
Drug dosages
Females
Fever
Hydronephrosis
Leukemia
Leukocytes
Lymphoma
Neurotoxicity
Neutropenia
Neutrophils
Nonsteroidal anti-inflammatory drugs
Patients
pediatric
Pediatrics
Radiation
Rhabdomyosarcoma
Sepsis
vincristine
Writing
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Summary:Background Fever is a common complaint among children with an underlying oncologic diagnosis, especially during chemotherapy courses and periods of neutropenia. Chemotherapy‐induced fever is well described in relation to specific chemotherapy agents. However, fever induced by vincristine (VCR) has only been rarely reported. Case We describe a case of a 5‐year‐old female with stage III Wilms tumor who had recurrent VCR‐associated fever that was controlled with prophylactic dexamethasone and acetaminophen. Conclusion In patients developing recurrent fever following chemotherapy with VCR, febrile allergic reaction and prophylactic treatment should be considered after exhaustion of appropriate investigations.
ISSN:2573-8348
2573-8348
DOI:10.1002/cnr2.1673