Hematological Abnormalities Beyond Lymphocytosis During Infectious Mononucleosis: Epstein-Barr Virus-Induced Thrombocytopenia

Thrombocytopenia during Epstein-Barr virus mononucleosis is well-known; however, no recent series have investigated its frequency, associated factors, and evolution. The present study aimed to investigate platelet count characteristics in adult patients with infectious mononucleosis. We reviewed the...

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Bibliographic Details
Published in:Mediterranean journal of hematology and infectious diseases 2023, Vol.15 (1), p.e2023023-e2023023
Main Authors: Páez-Guillán, Emilio-Manuel, Campos-Franco, Joaquín, Alende, Rosario, Gonzalez-Quintela, Arturo
Format: Article
Language:English
Subjects:
Blood platelets
Epstein Barr virus
Infectious mononuceosis
Original
Thrombocytopenia
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Summary:Thrombocytopenia during Epstein-Barr virus mononucleosis is well-known; however, no recent series have investigated its frequency, associated factors, and evolution. The present study aimed to investigate platelet count characteristics in adult patients with infectious mononucleosis. We reviewed the clinical records of 400 patients admitted to the hospital with infectious mononucleosis (52.0% male; median age, 19 years [range, 15-87 years]), focusing on blood platelet counts, thrombocytopenia prevalence and outcomes. Thrombocytopenia (platelet count ≤150 ×10 /L) was present in 119 (29.7%) patients. Thirty-two (8.0%) patients showed platelet counts lower than 100 ×10 /L. Thrombocytopenia was severe (platelets
ISSN:2035-3006
2035-3006
DOI:10.4084/MJHID.2023.023