Pulmonary tumor thrombotic microangiopathy in an unknown primary cancer

Pulmonary tumor thrombotic microangiopathy (PTTM) is a highly fatal complication of cancer leading to acute cor pulmonale and pulmonary hypertension. We present a case of 47-year-old male patient who developed acute breathlessness and died suddenly. The pulmonary vessels at autopsy on histopathologi...

Full description

Saved in:
Bibliographic Details
Published in:Lung India 2014-10, Vol.31 (4), p.410-412
Main Authors: Amonkar, Gayathri P, Jashnani, Kusum D, Pallewad, Sandhya
Format: Article
Language:English
Subjects:
Acute cor pulmonale
adenocarcinoma
carcinomatosis endarteritis
Care and treatment
Case Report
Case studies
Development and progression
Diagnosis
Lung cancer
pulmonary tumor thrombotic microangiopathy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Pulmonary tumor thrombotic microangiopathy (PTTM) is a highly fatal complication of cancer leading to acute cor pulmonale and pulmonary hypertension. We present a case of 47-year-old male patient who developed acute breathlessness and died suddenly. The pulmonary vessels at autopsy on histopathologic examination showed the presence of fibrocellular intimal proliferation, fibrin thrombi and few tumor emboli consisting of malignant adenocarcinoma cells. There was associated lymphangiosis carcinomatosis. No primary visceral tumor was found despite extensive search. The patient had died following acute cor pulmonale with sudden pulmonary hypertension due to PTTM. This entity (PTTM) must be kept as a differential diagnosis in patients presenting with acute breathlessness especially in cases of cancers.
ISSN:0970-2113
0974-598X
DOI:10.4103/0970-2113.142153