Time for Option B+? Prevalence and Characteristics of HIV Infection among Attendees of 2 Antenatal Clinics in Buea, Cameroon

As countries consider a wider use of triple antiretroviral therapy (ART) in pregnancy, which in recent World Health Organization guidelines is called Option B+, this study sought to explore the potential implications of adopting Option B+ by characterizing HIV infection in pregnant women attending 2...

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Bibliographic Details
Published in:Journal of the International Association of Providers of AIDS Care 2015-01, Vol.14 (1), p.77-81
Main Authors: Takow, Stephen Ekure, Atashili, Julius, Enow-Tanjong, Rebecca, Mesembe, Martha T., Ikomey, George M., Ndip, Lucy M., Mbuagbaw, Josephine C., Ndumbe, Peter M.
Format: Article
Language:English
Subjects:
Adult
Ambulatory Care Facilities
Anti-Retroviral Agents - administration & dosage
Anti-Retroviral Agents - therapeutic use
Antiretroviral drugs
Antiretroviral therapy
Cameroon - epidemiology
CD4 Lymphocyte Count
Cross-Sectional Studies
Female
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
Human immunodeficiency virus
Humans
Pregnancy
Pregnancy Complications, Infectious - drug therapy
Pregnancy Complications, Infectious - epidemiology
Prenatal Care
Prevalence
Viral Load
Women
Young Adult
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Summary:As countries consider a wider use of triple antiretroviral therapy (ART) in pregnancy, which in recent World Health Organization guidelines is called Option B+, this study sought to explore the potential implications of adopting Option B+ by characterizing HIV infection in pregnant women attending 2 semiurban antenatal clinics in Cameroon. In a descriptive cross-sectional study, consenting women were screened for HIV; positive samples were confirmed using an enzyme-linked immunosorbent assay test, and CD4 levels and HIV viral loads were determined using flow cytometry and reverse transcription–polymerase chain reaction, respectively. The seroprevalence of HIV in the 407 pregnant women screened was 8.4% (95% confidence interval: 5.9%-11.5%). The majority (82.4%) of HIV-positive women had CD4 counts >350 cells/mm3. A quarter (25%) had undetectable viral levels (
ISSN:2325-9574
2325-9582
2325-9582
DOI:10.1177/2325957413510607