Abdominal wall healing in incisional hernia using different biomaterials in rabbits

PURPOSE: To investigate abdominal wound healing using specific biomaterials in incisional hernias. METHODS: Incisional hernias were produced in 40 rabbits, after that they were reoperated with or without the use of meshes: PREMILENE® (PPL), ULTRAPRO® (UP), PROCEED® (PCD) or repairing without mesh (T...

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Bibliographic Details
Published in:Acta cirúrgica brasileira 2013-04, Vol.28 (4), p.307-316
Main Authors: Aramayo, Ana Letícia Gomes, Lopes Filho, Gaspar de Jesus, Barbosa, Cirênio de Almeida, Amaral, Vânia da Fonseca, Costa, Luciano Assis
Format: Article
Language:English
Subjects:
Abdominal Wall. Hernia, Ventral
Adhesions
Animal Experimentation
Biomaterials
Materials Testing
Rabbits
Surgical Mesh
Wound Healing
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Summary:PURPOSE: To investigate abdominal wound healing using specific biomaterials in incisional hernias. METHODS: Incisional hernias were produced in 40 rabbits, after that they were reoperated with or without the use of meshes: PREMILENE® (PPL), ULTRAPRO® (UP), PROCEED® (PCD) or repairing without mesh (TRANSPALB). After 30 days a macroscopic and microscopic study of the part withdrawn from the abdominal wall was performed. RESULTS: Macroscopic: adhesion Area: PPL> UP and PCD (p = 0.031). Vascularization: PPL> UP and PCD (p = 0.001). PPL groups (p = 0.032) and PCD (p PPL, UP and TRANSPALB (p = 0.010); eosinophils: PPL> UP, and TRANSPALB PCD (p = 0.010); granulation tissue: PPL and PCD> UP and TRANSPALB (p TRANSPALB (p UP (p = 0.009) and TRANSPALB (p TRANSPALB (p PCD and TRANSPALB (p
ISSN:0102-8650
0102-8650
DOI:10.1590/S0102-86502013000400011