Predictive value of hematological indices on incidence and severity of pulmonary embolism in COVID‐19 patients

BackgroundPulmonary thromboembolism (PTE) is a common complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which raises the COVID-19 disease's fatality rate from 3% to 45%. Nevertheless, due to fairly indistinguishable clinical symptoms and a lack of validated clinical...

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Published in:Immunity, Inflammation and Disease Inflammation and Disease, 2023-09, Vol.11 (9), p.e1012-e1012
Main Authors: Radkhah, Hanieh, Mansouri, Ensieh Sadat, Rahimipour Anaraki, Shiva , Gholizadeh Mesgarha, Milad, Sheikhy, Ali, Khadembashiri, Mohamad Mehdi, Khadembashiri, Mohamad Amin, Eslami, Mohamad, Mahmoodi, Tara, Inanloo, Behnaz, Pour Mohammad, Arash
Format: Article
Language:English
Subjects:
Blood
Blood platelets
Confidence intervals
COVID-19
Epidemics
Hematology
Hemoglobin
Leukemia
Leukocytes
Lymphocytes
Mortality
Neutrophils
neutrophil‐to‐lymphocyte ratio
Original
Pandemics
PESI score
platelet‐to‐lymphocyte ratio
Proteins
Pulmonary embolisms
pulmonary thromboembolism
Ratios
Regression analysis
SARS‐CoV‐2
Severe acute respiratory syndrome coronavirus 2
Statistical analysis
Thromboembolism
Variables
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Summary:BackgroundPulmonary thromboembolism (PTE) is a common complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which raises the COVID-19 disease's fatality rate from 3% to 45%. Nevertheless, due to fairly indistinguishable clinical symptoms and a lack of validated clinical prediction models, PTE diagnosis in COVID-19 patients is challenging. This study aims to investigate the applicability of hematological indices to predict PTE incidence and its severity in SARS-CoV-2 patients.MethodsA retrospective cohort study was conducted on hospitalized patients with a confirmed diagnosis of SARS-CoV-2 infection who underwent CT angiography to assess probable PTE in them. The correlation between complete blood count parameters 1 day before CT angiography and CT angiography outcomes, and simplified pulmonary embolism severity index (s-PESI) was investigated.ResultsWe discovered that among individuals with a probable PTE, males and those with higher platelet-to-lymphocyte (PLR) and neutrophil-to-lymphocyte (NLR) ratios had a greater likelihood of PTE incidence (p 
ISSN:2050-4527
2050-4527
DOI:10.1002/iid3.1012