QT Prolongation due to Graves’ Disease

Hyperthyroidism is a highly prevalent disease affecting over 4 million people in the US. The disease is associated with many cardiac complications including atrial fibrillation and also less commonly with ventricular tachycardia and fibrillation. Many cardiac pathologies have been extensively studie...

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Bibliographic Details
Published in:Case reports in cardiology 2017-01, Vol.2017 (2017), p.1-3
Main Authors: Manocha, Rohan, Tolly, Renee, Deol, Nisha, Kulairi, Zain, Naseer, Maliha
Format: Article
Language:English
Subjects:
Cardiac arrhythmia
Case Report
Electrocardiography
Family medical history
Gene expression
Heart rate
Hyperthyroidism
Mortality
Patients
Potassium
Studies
Thyroid gland
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Summary:Hyperthyroidism is a highly prevalent disease affecting over 4 million people in the US. The disease is associated with many cardiac complications including atrial fibrillation and also less commonly with ventricular tachycardia and fibrillation. Many cardiac pathologies have been extensively studied; however, the relationship between hyperthyroidism and rate of ventricular repolarization manifesting as a prolonged QTc interval is not well known. Prolonged QTc interval regardless of thyroid status is a risk factor for cardiovascular mortality and life-threatening ventricular arrhythmia. The mechanism regarding the prolongation of the QT interval in a hyperthyroid patient has not been extensively investigated although its clinical implications are relevant. Herein, we describe a case of prolonged QTc in a patient who presented with signs of hyperthyroidism that was corrected with return to euthyroid status.
ISSN:2090-6404
2090-6412
DOI:10.1155/2017/7612748