Hypertrophic pachymeningitis: case report

Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and de...

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Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2003-03, Vol.61 (1), p.107-111
Main Authors: de Deus-Silva, Leonardo, Queiroz, Luciano de Souza, Zanardi Vd, Verônica de Araújo, Ghizoni, Enrico, Pereira, Hoyama da Costa, Malveira, George Linard Silva, Pirani, Jr, Clodoaldo, Damasceno, Benito Pereira, Cendes, Fernando
Format: Article
Language:English
Subjects:
Biopsy
Dura Mater - pathology
Female
Gadolinium
Humans
hypertrophic pachymeningits
Hypertrophy
Magnetic Resonance Angiography
Meningitis - etiology
Meningitis - pathology
Middle Aged
Nasal Septum - pathology
neurosarcoidosis
NEUROSCIENCES
Optic Nerve Diseases - complications
optic neuropathy
PSYCHIATRY
psychosis
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Summary:Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.
ISSN:0004-282X
1678-4227
0004-282X
1678-4227
DOI:10.1590/s0004-282x2003000100021