Impact of addictive comorbidity on bipolar disorder type I

IntroductionAmong all mental pathologies, bipolar disorder (BD) is the one in which addictive comorbidity is most frequent.Recent studies suggest that this comorbidity has harmful consequences, threatening patients’ quality of life.ObjectivesDescribe addictive comorbidity and determine its prevalenc...

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Published in:European psychiatry 2024-08, Vol.67 (S1), p.S475-S475
Main Authors: Adouni, A, Zgueb, Y, F Ben Othman, Bouguerra, I, Jomli, R
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Language:English
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Addictive behaviors
Bipolar disorder
Comorbidity
Drug use
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creator Adouni, A
Zgueb, Y
F Ben Othman
Bouguerra, I
Jomli, R
description IntroductionAmong all mental pathologies, bipolar disorder (BD) is the one in which addictive comorbidity is most frequent.Recent studies suggest that this comorbidity has harmful consequences, threatening patients’ quality of life.ObjectivesDescribe addictive comorbidity and determine its prevalence in a population of patients with BD I.Study the impact of addictive comorbidity on the evolution of BD I.MethodsA cross-sectional, comparative study was conducted over a six-month period in the after-care unit of psychiatric wards at Razi Hospital, including patients treated for BD I according to DSM 5 criteria and stable on treatment.The study included two phases: first, sociodemographic, clinical and therapeutic characteristics were collected using a pre-established form. The CAGE, DUDIT and MARS scales, validated in Arabic, were then administered.ResultsWe included 100 patients (60 men and 40 women) with a mean age of 43.55 years.Substance use disorder (SUD) was reported in 31% of our population; 22 alcohol users with a mean CAGE score of 1.23 (0-3), while psychoactive substance use was reported in 19 patients with a mean DUDIT score of 13.37 (0-28).Forensic history was higher in the group of patients with comorbid SUD (p
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The CAGE, DUDIT and MARS scales, validated in Arabic, were then administered.ResultsWe included 100 patients (60 men and 40 women) with a mean age of 43.55 years.Substance use disorder (SUD) was reported in 31% of our population; 22 alcohol users with a mean CAGE score of 1.23 (0-3), while psychoactive substance use was reported in 19 patients with a mean DUDIT score of 13.37 (0-28).Forensic history was higher in the group of patients with comorbid SUD (p&lt;0.001). Poor compliance with treatment and irregular follow-up were also significantly more associated with addictive behavior, respectively p=0.008 and p=0.048.We found no association between SUD and suicidal behavior or evolutionary symptoms of the disorder.ConclusionsSUD are generally factors in the poor prognosis of BD. It is important to identify the determinants of this comorbidity, so that these risk factors can be appropriately targeted through appropriate therapeutic interventions and thus limit these negative consequences.Disclosure of InterestNone Declared</description><identifier>ISSN: 0924-9338</identifier><identifier>EISSN: 1778-3585</identifier><identifier>DOI: 10.1192/j.eurpsy.2024.985</identifier><language>eng</language><publisher>Paris: Cambridge University Press</publisher><subject>Addictive behaviors ; Bipolar disorder ; Comorbidity ; Drug use</subject><ispartof>European psychiatry, 2024-08, Vol.67 (S1), p.S475-S475</ispartof><rights>The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association. This work is licensed under the Creative Commons Attribution License This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Adouni, A</creatorcontrib><creatorcontrib>Zgueb, Y</creatorcontrib><creatorcontrib>F Ben Othman</creatorcontrib><creatorcontrib>Bouguerra, I</creatorcontrib><creatorcontrib>Jomli, R</creatorcontrib><title>Impact of addictive comorbidity on bipolar disorder type I</title><title>European psychiatry</title><description>IntroductionAmong all mental pathologies, bipolar disorder (BD) is the one in which addictive comorbidity is most frequent.Recent studies suggest that this comorbidity has harmful consequences, threatening patients’ quality of life.ObjectivesDescribe addictive comorbidity and determine its prevalence in a population of patients with BD I.Study the impact of addictive comorbidity on the evolution of BD I.MethodsA cross-sectional, comparative study was conducted over a six-month period in the after-care unit of psychiatric wards at Razi Hospital, including patients treated for BD I according to DSM 5 criteria and stable on treatment.The study included two phases: first, sociodemographic, clinical and therapeutic characteristics were collected using a pre-established form. The CAGE, DUDIT and MARS scales, validated in Arabic, were then administered.ResultsWe included 100 patients (60 men and 40 women) with a mean age of 43.55 years.Substance use disorder (SUD) was reported in 31% of our population; 22 alcohol users with a mean CAGE score of 1.23 (0-3), while psychoactive substance use was reported in 19 patients with a mean DUDIT score of 13.37 (0-28).Forensic history was higher in the group of patients with comorbid SUD (p&lt;0.001). Poor compliance with treatment and irregular follow-up were also significantly more associated with addictive behavior, respectively p=0.008 and p=0.048.We found no association between SUD and suicidal behavior or evolutionary symptoms of the disorder.ConclusionsSUD are generally factors in the poor prognosis of BD. It is important to identify the determinants of this comorbidity, so that these risk factors can be appropriately targeted through appropriate therapeutic interventions and thus limit these negative consequences.Disclosure of InterestNone Declared</description><subject>Addictive behaviors</subject><subject>Bipolar disorder</subject><subject>Comorbidity</subject><subject>Drug use</subject><issn>0924-9338</issn><issn>1778-3585</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNotzstKxDAYBeAgCo6jD-Au4Lr1z61J3MmgY2HAja5DbpWUmUlNO0Lf3uK4OnAW3zkI3ROoCdH0sa_jqQzjXFOgvNZKXKAVkVJVTChxiVagKa80Y-oa3YxjD0AkQLNCT-1hsH7CucM2hOSn9BOxz4dcXAppmnE-YpeGvLcFhzTmEmLB0zxE3N6iq87ux3j3n2v0-frysXmrdu_bdvO8qwJhUlSKcwFOExmBO0dAQGedi0FRHkQAz712UorGKQKO206qyDVQ1mjifSTA1qg9uyHb3gwlHWyZTbbJ_BW5fBlbpuT30TAGNASnqIgLQqj2nY5OQdc1y7xWi_VwtoaSv09xnEyfT-W43DcMtGSK8EaxX24IYt8</recordid><startdate>20240801</startdate><enddate>20240801</enddate><creator>Adouni, A</creator><creator>Zgueb, Y</creator><creator>F Ben Othman</creator><creator>Bouguerra, I</creator><creator>Jomli, R</creator><general>Cambridge University Press</general><scope>DOA</scope></search><sort><creationdate>20240801</creationdate><title>Impact of addictive comorbidity on bipolar disorder type I</title><author>Adouni, A ; Zgueb, Y ; F Ben Othman ; Bouguerra, I ; Jomli, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-d1375-84450b917e04bb1050fabbed824d5d0c4c9b7756b810b4af78e49023691cce103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Addictive behaviors</topic><topic>Bipolar disorder</topic><topic>Comorbidity</topic><topic>Drug use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adouni, A</creatorcontrib><creatorcontrib>Zgueb, Y</creatorcontrib><creatorcontrib>F Ben Othman</creatorcontrib><creatorcontrib>Bouguerra, I</creatorcontrib><creatorcontrib>Jomli, R</creatorcontrib><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>European psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adouni, A</au><au>Zgueb, Y</au><au>F Ben Othman</au><au>Bouguerra, I</au><au>Jomli, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of addictive comorbidity on bipolar disorder type I</atitle><jtitle>European psychiatry</jtitle><date>2024-08-01</date><risdate>2024</risdate><volume>67</volume><issue>S1</issue><spage>S475</spage><epage>S475</epage><pages>S475-S475</pages><issn>0924-9338</issn><eissn>1778-3585</eissn><abstract>IntroductionAmong all mental pathologies, bipolar disorder (BD) is the one in which addictive comorbidity is most frequent.Recent studies suggest that this comorbidity has harmful consequences, threatening patients’ quality of life.ObjectivesDescribe addictive comorbidity and determine its prevalence in a population of patients with BD I.Study the impact of addictive comorbidity on the evolution of BD I.MethodsA cross-sectional, comparative study was conducted over a six-month period in the after-care unit of psychiatric wards at Razi Hospital, including patients treated for BD I according to DSM 5 criteria and stable on treatment.The study included two phases: first, sociodemographic, clinical and therapeutic characteristics were collected using a pre-established form. The CAGE, DUDIT and MARS scales, validated in Arabic, were then administered.ResultsWe included 100 patients (60 men and 40 women) with a mean age of 43.55 years.Substance use disorder (SUD) was reported in 31% of our population; 22 alcohol users with a mean CAGE score of 1.23 (0-3), while psychoactive substance use was reported in 19 patients with a mean DUDIT score of 13.37 (0-28).Forensic history was higher in the group of patients with comorbid SUD (p&lt;0.001). Poor compliance with treatment and irregular follow-up were also significantly more associated with addictive behavior, respectively p=0.008 and p=0.048.We found no association between SUD and suicidal behavior or evolutionary symptoms of the disorder.ConclusionsSUD are generally factors in the poor prognosis of BD. It is important to identify the determinants of this comorbidity, so that these risk factors can be appropriately targeted through appropriate therapeutic interventions and thus limit these negative consequences.Disclosure of InterestNone Declared</abstract><cop>Paris</cop><pub>Cambridge University Press</pub><doi>10.1192/j.eurpsy.2024.985</doi><oa>free_for_read</oa></addata></record>
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subjects Addictive behaviors
Bipolar disorder
Comorbidity
Drug use
title Impact of addictive comorbidity on bipolar disorder type I
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