From Rarity to Recognition: Infantile Botulism and the Broad Spectrum of Differential Diagnoses

This case illustrates a 5-week-old girl who presented with decreased activity, decreased feeds, poor suck, weak cry, lethargy, hypotonia, and areflexia. The child was found to have infant botulism. The case demonstrates the importance of a full history and broad differential in an ill-appearing infa...

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Bibliographic Details
Published in:Case reports in pediatrics 2024, Vol.2024 (1), p.4647591
Main Authors: Authement, Matthew C., Jones, Brandon M., Kahoud, Robert J., Ristagno, Elizabeth H.
Format: Article
Language:English
Subjects:
Antibiotics
Babies
Botulinum toxin
Botulism
Case Report
Case reports
Congenital diseases
Constipation
Electrolytes
Emergency medical care
FDA approval
Glucose
Hospitalization
Hyperplasia
Hypothyroidism
Immunoglobulins
Medical diagnosis
Medical screening
Mitochondrial DNA
Newborn babies
Patients
Pediatrics
Prevention
Streptococcus infections
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Summary:This case illustrates a 5-week-old girl who presented with decreased activity, decreased feeds, poor suck, weak cry, lethargy, hypotonia, and areflexia. The child was found to have infant botulism. The case demonstrates the importance of a full history and broad differential in an ill-appearing infant. The differential for an ill-appearing infant should always include infectious etiologies and may include metabolic disorders, congenital anomalies, nonaccidental trauma, neurologic disorders, and endocrine disorders. The broad differential diagnosis may make rapid diagnosis and treatment for infantile botulism a challenge.
ISSN:2090-6803
2090-6811
DOI:10.1155/2024/4647591