Predictors for High-Risk Carotid Plaque in Asymptomatic Korean Population

Aims. High-risk carotid plaque remains an important risk factor for atherosclerotic cardiovascular disease (ASCVD). We sought to evaluate the characteristics of carotid plaque and to find out the predictors for high-risk carotid plaque in asymptomatic Koreans. Methods. Subjects (n=801) without a his...

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Bibliographic Details
Published in:Cardiovascular therapeutics 2020, Vol.2020 (2020), p.1-8
Main Authors: Lee, Moo-Sik, Chiara, Achangwa, Kim, Ki-Hong, Kim, Yong Kyun, Jang, Chae Won, Bae, Jang-Ho
Format: Article
Language:English
Subjects:
Adult
Age
Age Factors
Aged
Asymptomatic
Asymptomatic Diseases
Atherosclerosis
Blood pressure
Body mass index
Cardiovascular disease
Carotid arteries
Carotid Artery Diseases - diagnostic imaging
Carotid Artery Diseases - epidemiology
Cerebrovascular disease
Cholesterol
Coronary vessels
Demographics
Diabetes
Diabetes Mellitus - blood
Diabetes Mellitus - epidemiology
Fasting
Female
Glucose
Glycated Hemoglobin A - metabolism
Humans
Hypertension
Hypertension - epidemiology
Laboratories
Male
Middle Aged
Plaque, Atherosclerotic
Population
Prevalence
Professionals
Regression analysis
Republic of Korea - epidemiology
Retrospective Studies
Risk Assessment
Risk Factors
Sex Factors
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Summary:Aims. High-risk carotid plaque remains an important risk factor for atherosclerotic cardiovascular disease (ASCVD). We sought to evaluate the characteristics of carotid plaque and to find out the predictors for high-risk carotid plaque in asymptomatic Koreans. Methods. Subjects (n=801) without a history of ASCVD from 12 university hospitals in Korea underwent carotid ultrasound. The images were standardized at core laboratory. Morphologic characteristics of plaque were analyzed with laboratory and clinical characteristics. High-risk carotid plaque features included the highest quartile of carotid plaque score (cPS), irregular plaque surface, and hypoechoic and ulcerated plaque. Results. The carotid plaque prevalence was 22.1% (177/801 persons, 293 plaques). The plaque was increased with age (p
ISSN:1755-5914
1755-5922
DOI:10.1155/2020/6617506