Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China

We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. “Wisepill” uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC...

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Bibliographic Details
Published in:AIDS Research and Treatment 2013-01, Vol.2013 (2013), p.335-340
Main Authors: Keyi, Xu, Gifford, Allen L., Bachman DeSilva, Mary, Li, Zhong, Feng, Cheng, Brooks, Mohamad, Harrold, Mark, Yueying, Hu, Gill, Christopher J., Wubin, Xie, Vian, Taryn, Haberer, Jessica, Bangsberg, David, Sabin, Lora
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Behavior
Complications and side effects
Counseling
Developing countries
Drug therapy
Feasibility studies
Health aspects
HIV
HIV infection
Hospitals
Human immunodeficiency virus
Intervention
Intravenous drug abuse
LDCs
Patient compliance
Patients
Prevention
Public health
Real time
Risk factors
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Summary:We collected data on feasibility and acceptability of a real-time web-linked adherence monitoring container among HIV-positive injection drug users (IDU) in China. “Wisepill” uses wireless technology to track on-time medication dosing. Ten patients on antiretroviral therapy (ART) at the Guangxi CDC HIV clinic in Nanning, China, used Wisepill for one ART medication for one month. We monitored device use and adherence and explored acceptability of the device among patients. Mean adherence was 89.2% (SD 10.6%). Half of the subjects reported a positive overall experience with Wisepill. Seven said that it was inconvenient, supported by comments that it was large and conspicuous. Five worried about disclosure of HIV status due to the device; no disclosures were reported. Twelve signal lapses occurred (5.4% of prescribed doses), of which one was due to technical reasons, nine to behavioral reasons (both intentional and unintentional), and two to unclear reasons. Although the technical components must be monitored carefully, and acceptability to patients presents challenges which warrant further exploration, the Wisepill device has potential for adherence interventions that deliver rapid adherence-support behavioral feedback directly to patients, including IDU. The use of wireless technology appears uniquely promising for providing time-sensitive communication on patient behavior that can be harnessed to maximize the benefits of HIV treatment.
ISSN:2090-1240
2090-1259
DOI:10.1155/2013/957862