Prenatal marijuana exposure and neonatal outcomes: a retrospective cohort study

ObjectivesPrevious literature on the effects of marijuana exposure on neonatal outcomes has been limited by the reliance on maternal self-report. The objective of this study was to examine the relationship of prenatal marijuana exposure on neonatal outcomes in infants with marijuana exposure confirm...

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Bibliographic Details
Published in:BMJ open 2022-09, Vol.12 (9), p.e061167-e061167
Main Authors: Jones, Michael James, Lotfi, Asma, Lin, Amber, Gievers, Ladawna L, Hendrickson, Robert, Sheridan, David C
Format: Article
Language:English
Subjects:
Alcohol use
Apgar score
Birth weight
Cohort analysis
Diabetes
Drug use
Ethnicity
Feces
Gestational age
Hospital systems
Hospitals
Hypertension
Intensive care
Marijuana
Medical diagnosis
Missing data
NEONATOLOGY
Newborn babies
Paediatrics
Pediatrics
Pregnancy
Premature birth
Prenatal care
Prenatal diagnosis
Regression analysis
Substance misuse
Tetrahydrocannabinol
THC
Tobacco
Toxicology
Womens health
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Summary:ObjectivesPrevious literature on the effects of marijuana exposure on neonatal outcomes has been limited by the reliance on maternal self-report. The objective of this study was to examine the relationship of prenatal marijuana exposure on neonatal outcomes in infants with marijuana exposure confirmed with meconium drug testing.DesignRetrospective cohort study.Setting and participantsMeconium drug screens obtained on infants born in a hospital system in the Pacific Northwest in the USA over a 2.5-year period. 1804 meconium drug screens were initially obtained, with 1540 drug screens included in the analysis.Primary and secondary outcome measuresNeonates with meconium drug screens positive for delta-9-tetrahydrocannabinol (THC) only were compared with neonates with negative drug screens. The following neonatal outcomes were examined: gestational age, preterm birth (
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-061167