Current Understanding of Hydrogel for Drug Release and Tissue Engineering

Due to their good absorption, satisfactory biocompatibility, and high safety, hydrogels have been widely used in the field of biomedicine, including for drug delivery and tissue regeneration. In this review, we introduce the characteristics and crosslinking methods of natural and synthetic hydrogels...

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Bibliographic Details
Published in:Gels 2022-05, Vol.8 (5), p.301
Main Authors: Lei, Lanjie, Bai, Yujing, Qin, Xinyun, Liu, Juan, Huang, Wei, Lv, Qizhuang
Format: Article
Language:English
Subjects:
Biocompatibility
Crosslinking
Drug delivery systems
Drug dosages
drug release
Enzymes
Hyaluronic acid
Hydrogels
Hydrogen bonds
Mechanical properties
natural polymer
Polyethylene glycol
Polyvinyl alcohol
Radiation
Regeneration (physiology)
responsive hydrogels
Review
synthetic polymer
Synthetic products
Tissue engineering
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Summary:Due to their good absorption, satisfactory biocompatibility, and high safety, hydrogels have been widely used in the field of biomedicine, including for drug delivery and tissue regeneration. In this review, we introduce the characteristics and crosslinking methods of natural and synthetic hydrogels. Then, we highlight the design and principle of intelligent hydrogels (i.e., responsive hydrogels) used for drug release. Moreover, we introduce the application of the application of hydrogels in drug release and tissue engineering, and the limitations and research directions of hydrogel in drug release and tissue engineering are also considered. We hope that this review can provide a reference for follow-up studies in related fields.
ISSN:2310-2861
2310-2861
DOI:10.3390/gels8050301