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Simultaneous affinity maturation and developability enhancement using natural liability-free CDRs
ABBREVIATIONSCDR: complementarity determining region; FACS: fluorescence-activated cell sorting; ka: association rate; kd: dissociation rate; KD: dissociation constant; scFv: single-chain variable fragment; SPR: surface plasmon resonance.
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Published in: | mAbs 2022-12, Vol.14 (1), p.2115200-2115200 |
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Main Authors: | , , , , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | ABBREVIATIONSCDR: complementarity determining region; FACS: fluorescence-activated cell sorting; ka: association rate; kd: dissociation rate; KD: dissociation constant; scFv: single-chain variable fragment; SPR: surface plasmon resonance. |
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ISSN: | 1942-0862 1942-0870 |
DOI: | 10.1080/19420862.2022.2115200 |