What is the impact of local control in Ewing sarcoma: analysis of the first Brazilian collaborative study group - EWING1

Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control modality (surgery, surgery plus radiotherapy, and radiotherapy) on clinical outcomes such as survival and recurrence in patients with non-metastat...

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Bibliographic Details
Published in:BMC cancer 2017-06, Vol.17 (1), p.420-420, Article 420
Main Authors: Becker, Ricardo G, Gregianin, Lauro J, Galia, Carlos R, Jesus-Garcia Filho, Reynaldo, Toller, Eduardo A, Badell, Gerardo, Nakagawa, Suely A, David, Alexandre, Baptista, André M, Yonamime, Eduardo S, Serafini, Osvaldo A, Penna, Valter, Santos, Julie Francine C, Brunetto, Algemir L
Format: Article
Language:English
Subjects:
Adolescent
Adult
Bone cancer
Bone Neoplasms - mortality
Bone Neoplasms - pathology
Bone Neoplasms - therapy
Bone tumors
Brazil
Cancer therapies
Care and treatment
Chemotherapy
Child
Child, Preschool
Collaboration
Combined Modality Therapy
Diseases
Ewing sarcoma
Ewing's sarcoma
Ewings sarcoma
Female
Gangrene
Health aspects
Humans
Influence
Local control
Magnetic Resonance Imaging - methods
Male
Medical prognosis
Metastases
Neoplasm Metastasis
Neoplasm Staging
NMR
Nuclear magnetic resonance
Oncology
Orthopedics
Patients
Pediatrics
Prognosis
Proportional Hazards Models
Radiation oncology
Radiation therapy
Radiotherapy
Relapse
Risk factors
Sarcoma, Ewing - mortality
Sarcoma, Ewing - pathology
Sarcoma, Ewing - therapy
Studies
Surgery
Survival
Tomography, X-Ray Computed
Treatment Outcome
Tumor Burden
Tumors
Young Adult
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Summary:Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control modality (surgery, surgery plus radiotherapy, and radiotherapy) on clinical outcomes such as survival and recurrence in patients with non-metastatic Ewing sarcoma treated on the first Brazilian Collaborative Group Trial of the Ewing Family of Tumors (EWING1). Seventy-three patients with localized Ewing sarcoma of bone aged
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-017-3391-5