Pulmonary eosinophilic granulomatosis in a dog

A two-year-old female Prague Ratter dog was presented for evaluation of cough, exercise intolerance and worsening dyspnea. A previous treatment with antibiotics did not resolve the clinical signs. A diagnostic approach revealed peripheral eosinophilia, endoscopic bronchial changes, and bronchoalveol...

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Bibliographic Details
Published in:Veterinární medicína 2022-03, Vol.67 (3), p.150-155
Main Authors: Agudelo, Carlos Fernando, Stehlik, Ladislav, Filipejova, Zita, Koskova, Benicie, Sterbova, Marie, Crha, Michal
Format: Article
Language:English
Subjects:
allergy
Antibiotics
Azathioprine
Biopsy
bronchoalveolar lavage
Bronchus
Case Report
Computed tomography
Cough
Dogs
Dyspnea
Eosinophilia
Granuloma
Granulomatosis
immunosuppression
Intolerance
Leukocytes (eosinophilic)
Lungs
Prednisolone
Respiration
Thorax
tomography
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Summary:A two-year-old female Prague Ratter dog was presented for evaluation of cough, exercise intolerance and worsening dyspnea. A previous treatment with antibiotics did not resolve the clinical signs. A diagnostic approach revealed peripheral eosinophilia, endoscopic bronchial changes, and bronchoalveolar lavage with eosinophilic inflammation. Thoracic radiographs revealed a solitary mass and bilateral interstitial lung pattern. These radiographic findings were confirmed by computed tomography and ultrasound-guided biopsy of the lung mass. Treatment with prednisolone and azathioprine was initiated. Two months afterwards, the granuloma was no longer detectable radiographically. All medication was gradually discontinued after nine months and currently, after almost three years, the dog remains free of clinical signs.
ISSN:0375-8427
1805-9392
DOI:10.17221/136/2020-VETMED