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Constrictive Pericarditis Caused by IgG4-Related Disease Requiring Pericardiectomy After Partial Response to Corticosteroids

Immunoglobulin G4–related disease is a systemic fibroinflammatory disease; pericardial involvement has occasionally been reported in publications. A 79-year-old man with biopsy-proven immunoglobulin G4–related disease with pleural involvement was admitted in acute heart failure, with imaging and hem...

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Published in:JACC. Case reports 2020-08, Vol.2 (10), p.1558-1563
Main Authors: Yuriditsky, Eugene, Dwivedi, Aeshita, Narula, Navneet, Axel, Leon, Horowitz, James M., Vaynblat, Mikhail
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cited_by cdi_FETCH-LOGICAL-c3188-4cc91be60c5e5a8884d0904d28a1e479a8a7911f16484534110ec0034152f0153
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description Immunoglobulin G4–related disease is a systemic fibroinflammatory disease; pericardial involvement has occasionally been reported in publications. A 79-year-old man with biopsy-proven immunoglobulin G4–related disease with pleural involvement was admitted in acute heart failure, with imaging and hemodynamic studies consistent with constrictive pericarditis. He was treated with corticosteroids for 2 months with partial response manifest by decreases in pericardial thickening and immunoglobulin G4 levels. However, persistent constriction required pericardiectomy, leading to significant symptomatic improvement. (Level of Difficulty: Intermediate.) [Display omitted] Immunoglobulin G4–related disease is a systemic fibroinflammatory disease; pericardial involvement has occasionally been reported in publications. A…
doi_str_mv 10.1016/j.jaccas.2020.06.038
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subjects constrictive pericarditis
IgG4 related disease
Mini-Focus Issue: Heart Failure
title Constrictive Pericarditis Caused by IgG4-Related Disease Requiring Pericardiectomy After Partial Response to Corticosteroids
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